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Clinical Epidemiology. Practice and Methods
Parfrey, P.
1ª Edición Enero 2009
Inglés
Tapa dura
310 pags
1000 gr
null x null x null cm
ISBN 9781588299642
Editorial HUMANA PRESS
Clinical epidemiology provides the scientific basis for the practice of medicine due to its focus on the diagnosis, prognosis and management of human disease using appropriate research design, measurement and evaluation. In Clinical Epidemiology: Practice and Methods, leading experts contribute selections intended to educate researchers on how best to undertake clinical research. Divided into two categories, the volume first covers issues of design, measurement and analysis associated with various research designs, then continues with methods to better inform medical decision-making, including aggregation of multiple studies using meta-analysis, health economics, clinical practice guidelines and health technology assessment. As a part of the highly successful Methods in Molecular Biology™ series, this comprehensive text collects the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.
Essential and advantageous, Clinical Epidemiology: Practice and Methods is an ideal reference for medical practitioners, basic scientists and allied health professionals who desire to improve clinical outcomes.
Written for: Epidemiologists, medical practitioners, basic scientists, allied health professionals, and trainees in clinical epidemiology
Keywords:
- Clinical research
- Medical decision-making
- Research design
Table of contents
Chapter 1. On framing the research question and choosing the appropriate research
design.
Patrick Parfrey and Pietro Ravani
Chapter 2. Longitudinal studies and determination of risk.
Sean W. Murphy
Chapter 3. Modeling longitudinal data I: principles of multivariate analysis.
Pietro Ravani, Brendan Barrett and Patrick Parfrey
Chapter 4. Modeling longitudinal data II: standard regression models and extensions.
Pietro Ravani, Brendan Barrett and Patrick Parfrey
Chapter 5. The design of randomized controlled trials.
Bryan M. Curtis, Brendan Barrett and Patrick Parfrey
Chapter 6. Analysis of randomized controlled clinical trials.
Robert N. Foley
Chapter 7. Evaluation of diagnostic tests.
John M. Fardy
Chapter 8. Biomarkers and surrogates in clinical studies.
Claudio Rigatto and Brendan Barrett
Chapter 9. Measurement and analysis of patient-reported outcomes
Klemens B. Meyer and Kimberly A. Clayton
Chapter 10. Bias in clinical studies of genetic diseases
Susan Stuckless and Patrick Parfrey
Chapter 11. Genetic Epidemiology of Complex Phenotypes
Lynette Peddle and Proton Rahman
Chapter 12. Qualitative research in clinical epidemiology
Deborah M. Gregory and Christine Way
Chapter 13. Primer on Systematic Review and Meta-analysis
Marcello Tonelli, Dan Hackman and Amit X. Garg
Chapter 14. The role of health economics within clinical research
Braden J. Manns
Chapter 15. Development and limitations of clinical practice guidelines
Bruce Culleton
Chapter 16. Basics of Health Technology Assessment
Daria O’Reilly, Kaitryn Campbell and Ron Goeree
Chapter 17. Research Ethics for clinical researchers
John D. Harnett and Richard Neuman
Chapter 18. Budgeting, funding and managing clinical research projects
Elizabeth Hatfield, Elizabeth Dicks and Patrick Parfrey
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