Contemporary Endocrinology: Energy Metabolism and Obesity

About this book
Energy Metabolism and Obesity: Research and Clinical Applications is a compilation of highly informative reviews written by undisputed leaders in the field. These authors elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them. Understanding the physiology of energy storage and partitioning has become quite a daunting task. This title enables researchers and clinicians to face the challenge of understanding this complex topic and applying the information to the practice of obesity prevention and treatment. The excellent overviews in this book will undoubtedly provide readers with a better understanding of the multifaceted entity of obesity.

Written for: Endocrinologists, diabetes specialists, internists, family practitioners

Keywords:

• Balance
• Energy
• Insulin Resistance
• Molecular
• Obesity

Table of Contents

Contemporary Endocrinology
Energy Metabolism and Obesity: Research and Clinical Applications

Editor: Patricia A. Donohoue, MD, Professor of Pediatrics, Division of Endocrinology and Diabetes
University of Iowa Carver College of Medicine
Children’s Hospital of Iowa at University of Iowa Hospitals and Clinics
200 Hawkins Drive, 2858 JPP
Iowa City, IA 52242-1083
Phone 319-356-3164
FAX 319-356-8170

Chapter 1: Molecular Physiology of Monogenic and Syndromic Obesities in Humans-Wendy K. Chung and Rudolph L. Leibel

Chapter 2 : Leptin Signaling In the Brain-Ofer Reizes, Stephen C. Benoit, and Deborah J. Clegg

Chapter 3: Inactivating Melanocortin-4 Receptor Mutations and Human Obesity-Ya-Xiong Tao

Chapter 4: The Role of Central Melanocortins in Cachexia-Daniel L. Marks

Chapter 5: The Efferent Arm of the Energy Balance Regulatory Pathway:Neuroendocrinology and Pathology-Robert H. Lustig

Chapter 6: Adiponectin: A Multifunctional Adipokine-Kristen Clarke and Robert L. Judd

Chapter 7: The Role of the Gastrointestinal Hormones Ghrelin, Peptide YY and Glucagon-like Peptide-1 in the Regulation of Energy Balance-Ruben Nogueiras, Hilary Wilson, Diego Perez-Tilve and Matthias H. Tschöp

Chapter 8: The Role of GHSs/Ghrelin in Feeding and Body Composition-Cyril Y. Bowers, Blandine Laferrere, David Hurley, and Johannes D. Veldhuis

Chapter 9: Interaction Between Physical Activity and Genetic Factors in Complex Metabolic Disease-Paul W. Franks and Stephen M. Roth

Chapter 10: 11ß-Hydroxysteroid Dehydrogenase Type 1 and Obesity-Roland H. Stimson and Brian R. Walker

Chapter 11: Prader-Willi Syndrome (PWS): A Model of Disordered Energy Homeostasis-Andrea Haqq

Chapter 12: Antipsychotic Medication-Induced Weight Gain and Risk for Diabetes and Cardiovascular Disease-John W. Newcomer

Chapter 13: Treatment of Insulin Resistance in Youth:The Role of Metformin-Molly Emott and Michael Freemark

Chapter 14: The Surgical Approach to Morbid Obesity-Edward E. Mason, Mohammad K. Jamal and Thomas O’Dorisio