Heart Disease and Erectile Dysfunction

Senior physicians, cardiologists, urologists, psychologists, and pharmacologists critically review the relation between heart disease and erectile dysfunction (ED) and explain for the practicing physician the effective new treatment options available for the cardiac patient with ED. The authors detail in concise language the latest thinking about the risk of sexually induced cardiac events, the efficacy and risks to cardiac patients of drugs used to treat sexual dysfunction, and the expert guidelines developed by prominent organizations on the optimal approach to sexual dysfunction in the cardiac patient. They also discuss the physiology of ED and the currently available therapies (sildenafil, tadalafil, and vardenafil) may interact with the cardiac system, and the potential application of newer agents like phosphodiesterase-5 inhibitors to cardiovascular disease.

Contents: Physiology of Erection and Causes of Erectile Dysfunction - Aristotelis G. Anastasiadis, Dmitry Droggin, Martin Burchardt, and Ridwan Shabsigh; Erectile Dysfunction: The Scope of the Problem - Culley C. Carson, III; Erectile Dysfunction and Cardiovascular Risk Factors - Robert A. Kloner; Psychologic Aspects of Erectile Dysfunction in Heart Patients - Raymond C. Rosen; Management of Erectile Dysfunction: An Overview - Harin Padma-Nathan; Sildenafil Citrate and the NO/cGMP Signaling Pathway - Ian H. Osterloh and Stephen C. Phillips; PDE5 Inhibition: Importance to the Cardiovascular System - Jackie D. Corbin, Stephen R. Rannels, and Sharron H. Francis; The Hemodynamics of PDE5 Inhibitors - Graham Jackson; Cardiovascular Safety of PDE5 Inhibitors - Robert A. Kloner; Effect of PDE5 Inhibition on Coronary Blood Flow in Experimental Animals - YingJie Chen, Jay H. Traverse, and Robert J. Bache; Cardiac Effects of Non-PDE5 Inhibitor Erectile Dysfunction Therapies - Harin Padma-Nathan; PDE5 Inhibition in Coronary Patients - Sameer Rohatgi and Howard C. Herrmann; Potential Cardiac Applications of PDE5 Inhibition - Michael Sweeney and Richard L. Siegel; The Physiologic Cost of Sexual Activity - Robert F. DeBusk; Sexual Activity as a Trigger of Myocardial Infarction/Ischemia: Implications for Treating Erectile Dysfunction - Robert A. Kloner; Sex after Cardiac Events and Procedures: Counseling from the Cardiovascular Specialist's Perpective - Herman A. Taylor, Jr.; American College of Cardiology / American Heart Association Guidelines on the Use of Sildenafile in Patients with Cardiovascular Disease - Adolph M. Hutter, Jr.; Risk of Heart Attack after Sexual Activity: The Princeton Guidelines and Their Rationale - Robert F. DeBusk