Principles of Molecular Cardiology

This text provides a look into the advances in the fields of molecular biology, development and genetics in relation to cardiology. It offers to the reader an introduction to molecular cardiology via a section of introductory overviews. The authors provide chapters on disease-oriented topics written by leaders in the field. Theses experts have gathered a concise and thorough discussion of the relevant molecular, cellular, genetic and developmental biological processes that underlie and contribute to cardiovascular disease. Principles of Molecular Cardiology, presents a reference that any scientist in the field would want to own as a broad overview of the field. Also a valuable tool to any cardiology fellow would benefit from due to the insights it provides into the common diseases in the field

Contents: Part I. Overview Cardiovascular Genetics Christopher Semsarian and Christine Seidman Molecular Biology Applications in Cardiovascular Medicine Eugene Yang, Scott M. Wasserman, Tatsuro Ishida, Raymond Tabibiazar, and Thomas Quertermous Genomics and Its Application to Cardiovascular Disease Robert Roberts Gene Therapy and Cardiovascular Diseases Yi Chu, Neal L. Weintraub, and Donald D. Heistad Stem Cells and Progenitor Cells in Cardiovascular Disease Jalees Rehman and Keith L. March Part II. Myocardial Disease Development of the Vertebrate Heart Mabelle Ashe and David Bader Inherited Myocardial Diseases Elizabeth M. McNally Receptor-Signaling Pathways in Heart Failure Shayela Suvarna, Liza Barki-Harrington, Miwako Suzuki, Philippe Le Corvoisier, and Howard A. Rockman Recent Insights into the Molecular Pathophysiology of Viral Myocarditis Tony Tran, Roger D. Rossen, and Douglas L. Mann Genetic Underpinnings of Cardiogenesis and Congenital Heart Disease Vidu Garg and Deepak Srivastava Part III. Coronary Artery Disease Coronary Artery Development Mark W. Majesky Atherosclerosis George A. Stouffer Antiplatelet Drugs Karlheinz Peter Myocardial Infarction D. Douglas Miller and Steven C. Herrmann Transplant Arteriopathy: Pathology, Pathogenesis, and Prospects for Treatment Joannis Vamvakopoulos, Einari Aavik, Daniel du Toit, Pekka Hayry, and Minnie Sarwal Thrombolysis: Scientific Basis for Current Theory Guy L. Reed III Coronary Restenosis Julius Aitsebaomo, Martin Moser, Susan Smyth, and Cam Patterson Part IV. Arrhythmias Induction and Patterning of Purkinje Fiber Network Takashi Mikawa, Robert G. Gourdie, Kimiko Takebayashi-Suzuki, Nobuyuki Kanzawa, David J. Pennisi, Clifton P. Poma, and Maxim Shulimovich Mechanisms of Sudden Cardiac Death Wayne E. Cascio Gene Therapy for Cardiac Arrhythmias J. Kevin Donahue and Eduardo Marban Genetics and Arrhythmias Kui Hong and Ramon Brugada Part V. Vascular Diseases Therapeutic Angiogenesis for Ischemic Vascular Disease Jai Pal Singh and J. Anthony Ware Nitric Oxide in Cardiovascular Biology and Pathophysiology Marshall A. Corson Vasculitis Ronald J. Falk and J. Charles Jennette Primary Pulmonary Hypertension Evangelos D. Michelakis and Stephen L. Archer The Molecular Basis of Cerebrovascular Malformations Douglas A. Marchuk Thrombotic Vascular Disease Stephan Moll and Gilbert C. White II Part VI. Risk Factors Risk Factors Ngoc-Anh Le and W. Virgil Brown Vascular Aging: From Molecular to Clinical Cardiology Samer S. Najjar and Edward G. Lakatta Oxidative Stress Nageswara R. Madamanchi and Marschall S. Runge Diabetes Mellitus: An Important Cardiovascular Risk Factor David R. Clemmons Vascular Inflammation as a Cardiovascular Risk Factor Allan R. Brasier and Adrian Recinos III, and Mohsen S. Eledrisi