Raynaud's Phenomenon. a Guide to Pathogenesis and Treatment

Description

Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike. In the last decade, there have been important advances not only in understanding the pathophysiology of Raynaud’s Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies. Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP. The work offers differential diagnosis options, reviews potential causes such as autoimmune disease, industrial trauma, drugs, and metabolic causes and provides clear recommendations for therapy. Engaging readers with case vignettes and a plethora of visual aids, Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes.

Feature

• Renowned experts on Raynaud’s Phenomenon offer comprehensive review and new insights into this disorder
• Reviews current understanding of pathogenesis, methods of measuring Raynaud’s Phenomenon, and current treatment options
• Of interest to healthcare providers who deal with Raynaud’s Phenomenon and associated diseases and to scientists interested in this disorder

Table of Contents

Chapter 1 Historical perspective of Raynaud’s phenomenon
Andrea Fava and Francesco Boin

Chapter 2 Definition, Nomenclature, And Diagnostic Criteria
Serena Guiducci & Marco Matucci Cerinic

Chapter 3 Epidemiology of Raynaud’s Phenomenon
Adam Maundrell, Susanna M. Proudman

Chapter 4 Thermoregulation: The Normal Structure and Function of the Cutaneous Vascular System
Nicholas A. Flavahan

Chapter 5 Pathophysiological Regulation of the Cutaneous Vascular System in Raynaud’s Phenomenon
Nicholas A. Flavahan

Chapter 6 Primary Raynaud’s Phenomenon
Ariane L. Herrick

Chapter 7 Raynaud Phenomenon In The Pediatric Age
Francesco Zulian, Clare Pain

Chapter 8 Secondary Raynaud’s phenomenon
Voon H. Ong, Christopher P. Denton

Chapter 9 Traumatic Vasospastic Disease
Ami A. Shah

Chapter 10 Other Secondary Causes
Marina Anderson, Michael Hughes

Chapter 11 Raynaud’s Mimics
Zsuzsanna H. McMahan and Julie Paik

Chapter 12 Nailfold Capillaries
Maurizio Cutolo and Vanessa Smith

Chapter 13 Non-Invasive methods of assessing Raynaud’s phenomenon
Andrea Murray and John D. Pauling

Chapter 14 Angiography
Yannick Allanore, Jean-Luc Drappé, Thomas Reifsnyder

Chapter 15 Autoantibodies in Raynaud’s Phenomenon
Victoria Flower, John. D. Pauling, Neil McHugh

Chapter 16 Systemic Vasospasm
Laura K. Hummers

Chapter 17 Clinical Outcome Measures in Raynaud’s Phenomenon
Dinesh Khanna, Heather Gladue, James R. Seibold

Chapter 18 Design and reporting of randomised controlled trials for Raynaud’s phenomenon
Jack Wilkinson

Chapter 19 Non-drug Approaches to Treating Raynaud’s Phenomenon
Linda Kwakkenbos, Brett D. Thombs

Chapter 20 Drug Treatment of Raynaud’s Phenomenon
Janet E. Pope

Chapter 21 Management of digital ischemia
Antonia Valenzuela, Rasidat Adeduntan, Lorinda Chung

Chapter 22 Surgical Management
Lindsay Muir

Chapter 23 Practical Approaches to Treatment: Case Studies
Fredrick M. Wigley