Atlas of Time Lapse Embryology

Description

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo’s in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances of a positive outcome.

The Atlas of Time Lapse Embryology describes in detail the technology and techniques surrounding time lapse embryology. The book also covers the clinical aspects of time lapse imaging, morphokinetic timings, implantation data, fertilization, compaction, blastulation, irregular cleavages, multinucleation, vacuolation, zona defects, and other topics.

The book is easy to read, practical, and illustrated with dozens of images and video clips to help explain a variety of concepts. It will help practitioners to better understand how time lapse monitoring may dramatically increase flexibility in the IVF clinic, and most importantly, enhance clinical outcomes.

Features

• Explains a new technology which helps in selecting the most viable embryos from a cohort and increases the chances of a positive outcome
• Includes material on equipment and clinical aspects
• Features illustrations with enlarged images, sequences, and video clips
• Incorporates the patient perspective
• Written by world-leading experts on the technique

Table of Contents

Equipment Required for Time Lapse Observations in In Vitro Fertilization; Louise Best
Clinical Aspects of Time Lapse Imaging; Alison Campbell
Time Lapse, the Cell Cycle, Distribution of Morphokinetic Timings, and Known Implantation Data; Alison Campbell
Gender and Morphokinetics Correlation; Samantha Duffy
Polar-Body Extrusion; Colleen Lynch and Mercedes Reguiera
Fertilization: Pronuclear Formation and Fading; Louise Kellam and Laina Murphy
Clinical Results: Dynamic Aspects—Fragmentation; Sue Montgomery
Number of Pronuclei and Ploidy in IVF /ICSI—Derived Embryos; Abigail A. Burchill
Dynamic Aspects: Compaction; Sue Montgomery
Blastulation; Sue Montgomery
Hatching of the Human Blastocyst; Louise Kellam
Irregular Cleavages; Kathryn Berrisford and Ellen Cater
Reverse Cleavage/Blastomere Fusion; Davina Hulme
Smooth Endoplasmic Reticulum Clusters; Cath Drezet
Multinucleation; Claire Shearer
Vacuolation; Rachel Smith
Granular Cytoplasm; Sarah Foley
Zona Defects; Gerri Emerson
The Patient Perspective; Samantha Duffy

Author(s) Bio

Alison Campbell, M. Med. Sci, head of embryology, CARE Fertility Group, Nottingham, UK
Simon Fishel, PhD, professor of human reproduction and CEO, CARE Fertility Group, Nottingham, UK