Physics of Pet and Spect Imaging

Description

PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitativetechniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.

Features

• Provides a single, comprehensive and authoritative account of PET and SPECT instrumentation, correction techniques, image reconstruction, multimodality and preclinical imaging
• Includes a background section that gives the foundation of PET and SPECT physics
• Gives a detailed summary of detector technology, from basics of scintillators, photodetectors, and solid state detectors, to the state of the art in PET and SPECT instrumentation
• Discusses quantitative imaging aspects, from PET and SPECT corrections to image reconstruction, dynamic PET and SPECT, and whole body PET
• Covers multimodality imaging in detail, including PET/CT, SPECT/CT, PET/MRI, and SPECT/MRI, as well as preclinical PET and SPECT

 

Contents

Part 1 BASICS

Principles of SPECT and PET Imaging 
Magnus Dahlbom and Michael A. King

Part 2 TECHNOLOGY

Scintillators for PET and SPECT
Charles L. Melcher and Lars Eriksson

Photodetectors
Magnus Dahlbom

Acquisition Electronics
Thomas K. Lewellen

SPECT Instrumentation
Wei Chang, Michael Rozler, and Scott D. Metzler

PET Instrumentation
Andrew L. Goertzen and Jonathan D. Thiessen

PART 3 QUANTITATIVE IMAGING

Methodologies for Quantitative SPECT
Irène Buvat

Data Corrections and Quantitative PET
Suleman Surti and Joshua Scheuermann

Image Reconstruction for PET and SPECT
Richard M. Leahy, Bing Bai, and Evren Asma

High-Performance Computing in Emission Tomography
Guillem Pratx

Methods and Applications of Dynamic SPECT Imaging 
Anna M. Celler, Troy H. Farncombe, Alvin Ihsani, Arkadiusz Sitek, and R. Glenn Wells

Dynamic PET Imaging 
Sung-Cheng (Henry) Huang and Koon-Pong Wong

Part 4 MULTIMODALITY IMAGING

PET/CT 
Søren Holm, Osama Mawlawi, and Thomas Beyer

SPECT/CT 
Yothin Rakvongthai, Jinsong Ouyang, and Georges El Fakhri

PET/MRI 
Ciprian Catana

Part 5 PRECLINICAL IMAGING AND CLINICAL APPLICATIONS

Preclinical PET and SPECT 
Steven R. Meikle, Andre Z. Kyme, Peter Kench, Frederic Boisson, and Arvind Parmar

Clinical Applications of PET/CT and SPECT/CT Imaging 
Johannes Czernin and Ora Israel, Ken Herrmann, Martin Barrio, David Nathanson, and Martin Allen-Auerbach

Editor(s) Bio

Magnus Dahlbom has been working in the field of Nuclear Medicine for close to 30 years. He earned his B.Sc. in physics from the University of Stockholm in 1982. He received his Ph.D. from UCLA in 1987. His Ph.D. research was on high-resolution PET detectors and image processing. In 1989 he was part of the team that started the first clinical PET operation in the U.S. at UCLA. Around the same time developed together with Drs. Edward J. Hoffman and Michael E. Phelps the Whole Body PET imaging technique, whichcurrently makes up more than 90% of all PET studies performed. His research interests are in PET and SPECT instrumentation and image processing. Since 1989 he has been the chief physicist at the Nuclear Medicine services at UCLA where he is responsible forall imaging instrumentation, including SPECT, SPECT/CT and PET/CT systems. At UCLA he is the faculty graduate advisor in the Biomedical Physics graduate program. He is teaching graduate level courses on the basics of Nuclear Medicine imaging and instrumentation. He has authored and co-authored more than 120 research papers and 11 book chapters on nuclear imaging instrumentation and processing. He was also co-editor of a PET/CT atlas. For the last 6 years he has been serving as an editorial consultant to the editor-in-chief of the Journal of Nuclear Medicine.