Biochemistry. a Short Course (International Edition)

Table of contents

PART I: THE MOLECULAR DESIGN OF LIFE

• Biochemistry Helps Us Understand Our World
• Biochemistry and the Unity of Life
• Water, Weak Bonds, and the Generation of Order Out of Chaos
• Protein Composition and Structure
• Amino Acids
• Protein Three-Dimensional Structure
• Basic Concepts and Kinetics of Enzymes
• Basic Concepts of Enzyme Action Kinetics and Regulation Mechanisms and Inhibitors
• Hemoglobin, an Allosteric Protein
• Carbohydrates and Lipids
• Carbohydrates
• Lipids
• Cell Membranes, Channels, Pumps, and Receptors
• Membrane Structure and Function
• Signal-Transduction Pathways

PART II: TRANSDUCING AND STORING ENERGY

• Basic Concepts and Design of Metabolism Digestion: Turning a Meal into Cellular Biochemicals
• Metabolism: Basic Concepts and Design
• Glycolysis and Gluconeogenesis
• Glycolysis
• Gluconeogenesis
• The Citric Acid Cycle
• Preparation for the Cycle
• Harvesting Electrons from the Cycle
• Oxidative Phosphorylation
• The Electron-Transport Chain
• The Proton-Motive Force
• The Light Reactions of Photosynthesis and the Calvin Cycle
• The Light Reactions The Calvin Cycle
• Glycogen Metabolism and the Pentose Phosphate Pathway
• Glycogen Degradation
• Glycogen Synthesis
• The Pentose Phosphate Pathway
• Fatty Acid and Lipid Metabolism
• Fatty Acid Degradation
• Fatty Acid Synthesis
• Lipid Synthesis: Storage Lipids, Phospholipids, and Cholesterol
• The Metabolism of Nitrogen-Containing Molecules
• Amino Acid Synthesis
• Nucleotide Metabolism
• Amino Acid Degradation and the Urea Cycle

PART III: SYNTHESIZING THE MOLECULES OF LIFE

• Nucleic Acid Structure and DNA Replication
• The Structure of Informational Macromolecules: DNA and RNA
• DNA Replication
• DNA Repair and Recombination
• RNA Synthesis, Processing, and Regulation
• RNA Synthesis and Regulation in Prokaryotes
• Gene Expression in Eukaryotes
• RNA Processing in Eukaryotes
• Protein Synthesis
• The Genetic Code
• The Mechanism of Protein Synthesis

PART IV: EXPERIMENTAL BIOCHEMISTRY

• Techniques in Protein Biochemistry
• Immunological and Recombinant DNA Techniques

Author Biography

JOHN L. TYMOCZKO Towsley Professor of Biology at Carleton College, USA. JEREMY M. BERG was Professor and Director of the Department of Biophysics and Biophysical Chemistry at Johns Hopkins University School of Medicine, USA, where he remained until 2003. He then became Director of the National Institute of General Medical Sciences at the National Institutes of Health. LUBERT STRYER Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, USA, where he has been on the faculty since 1976. The publication of his first edition of Biochemistry in 1975 transformed the teaching of Biochemistry.