Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction. Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family. Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids. Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose, and replacement therapy. This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.
Foreward Russell K. Portenoy MD Preface Ricardo A. Cruciani, MD, PhD & Helena Knotkova, PhD Prescribing Methadone SafelyEliezer Soto MD, Joy Hao MD, PhD, Helena Knotkova PhD, Ricardo A. Cruciani MD, PhD Use of Methadone in Opioid Maintenance TreatmentDr. Randy M. Seewald, MBBS Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence Daniel P. Alford, MD, MPH, Declan T. Barry, PhD, & David A. Fiellin, MD Methadone Side Effects: Constipation, Respiratory Depression, Sedation, Sleep-Disordered Breathing, and the Endocrine SystemLynn R. Webster, MD Cardiovascular Effects of MethadoneMiguel A. Leal, MD & Craig T. January, MD, PhD Methadone Pharmacodynamics and PharmacokineticsGavin Bart, MD & Sharon L. Walsh PhD Methadone and opioid rotationHelena Knotkova PhD, Ricardo A. Cruciani,MD, PhD, Perry G. Fine MD Intravenous use of Methadone: efficacy and safetySebastiano Mercadante, MD Methadone HyperalgesiaPeggy Compton, RN, PhD, FAAN Buprenorphine Analgesia in Chronic PainGuy Hans, MD, PhD Buprenorphine in Maintenance TherapyKarran A. Phillips, MD, MSc & Kenzie L. Preston, PhD Buprenorphine Pharmacodynamics and PharmacokineticsSharon L. Walsh, PhD & Lisa S. Middleton, PhD 13. Buprenorphine metabolism and drug-drug interactions Robert Taylor Jr., PhD, Robert B. Raffa, PhD, & Joseph V. Pergolizzi Jr., MD Buprenorphine: side effects and tolerabilityTabitha Washington, MD, MS & Gilbert J. Fanciullo, MD, MS Buprenorphine and Opioid RotationDouglas L. Gourlay, MD, MSc, FRCP, FASAM & Howard A. Heit MD, FACP, FASAM Methadone and buprenorphine use during the perinatal periodAlice Ordean MD, CCFP, MHSc Methadone and Buprenorphine Prescribing in the Palliative Care PopulationShalini Dalal MD & Eduardo Bruera MD Methadone Prescribing In The Sickle Cell PatientWally R. Smith, MD & Abdulkhaliq J. Alsalman, MS Methadone and Buprenorphine Analgesia in Older PatientsDavid Lussier, MD, FRCP(c)