Human Immunodeficiency Virus Type 1 (HIV-1) and Breastfeeding. Science, Research Advances, and Policy (Advances in Experimental Medicine and Biology)

ABOUT THIS BOOK

• Presents the scope of HIV transmission from mother to infant through breast milk
• Includes new discoveries of mucosal and innate immunity
• Gives a current look at international research that attempts to balance HIV transmission prevention with retaining breast milk’s nutritional and immunologic benefits

Content Level » Research
Related subjects » Immunology - Internal Medicine - Medicine - Public Health - Virology

TABLE OF CONTENTS

• Breastfeeding and transmission of HIV-1: Epidemiology and Global Magnitude.
• Breastfeeding and Transmission of viruses other than HIV-1.
• Breastfeeding among HIV-1-infected women: Maternal health outcomes and social repercussions.
• Virologic determinants of breast milk transmission of HIV-1.
• HIV-1 resistance to antiretroviral agents: Relevance to mothers and infants in the breastfeeding setting.
• Animal models of HIV transmission through breastfeeding and pediatric HIV infection.
• Antiretroviral pharmacology in breast milk.
• HIV-1 diagnosis of the breastfed infant.
• The immune system of breast milk: antimicrobial and anti-inflammatory properties.
• Humoral /mucosal/innate immunity in the breast milk in the context of HIV-1 infection.
• Cellular immunity in breast milk: Implications for Postnatal Transmission of HIV-1 to the infant.
• Antiretroviral drugs during breastfeeding for the prevention of postnatal transmission of HIV-1.
• Immune Approaches for the prevention of breast milk transmission of HIV-1.
• Non-antiretroviral approaches to prevention of breast milk transmission of HIV-1: Exclusive breastfeeding, early weaning, treatment of expressed breast milk.
• Breast milk micronutrients and mother-to-child transmission of HIV-1.
• Historical perspective of African-based research on HIV-1 transmission through breastfeeding: The Malawi experience.
• Breastfeeding and HIV infection in China.
• The role of the President’s Emergency Plan for AIDS Relief (PEPFAR) in infant and young child feeding guideline development and program implementation.
• Should women with HIV-1 infection breastfeed their infants? Balancing the scientific evidence, ethical issues and costs-policy considerations.
• HIV-1 and Breastfeeding in the United States.
• Epilogue. The future of breastfeeding in the face of HIV-1 infection: Science and Policy.