Acute Leukemia, an Issue of Hematology/oncology Clinics of North America, Vol. 25-6

DESCRIPTION

Topics for this issue will include: CLL: A Historical Perspective; Incidence & Epidemiology;Biology , Molecular Biology & Cytogenetics of CLL; What does the status of smatic hypermutations in IGVH genes tell us about the origin of CLL? ;What does the status of ZAP-70 tell us about the biology of CLL?;and Approach to initial therapy: When to start therapy?

AUTHOR

By Martin Tallman, MD, Chief, Leukemia ServiceMemorial Sloan Kettering Cancer CenterProfessor of MedicineWeill Cornell Medical CollegeNew York, NY