Antibiotics in Laboratory Medicine

Description

Antibiotics in Laboratory Medicine has been the defining reference source on evaluating the effectiveness of antibiotic compounds in treating infectious diseases for over 35 years. This thoroughly updated 6th Edition, edited by Daniel Amsterdam and featuring contributions from an elite team of leading international experts, equips you with all the latest methods for analyzing the mechanisms of activity/resistance of various pathogens, assessing their susceptibility to potential treatments, and detecting drug resistance and multi-drug resistance.

• New chapters explore the predictive value of in vitro laboratory testing, the challenges of developing antimicrobial stewardship, and the improvements in inpatient care that antimicrobial stewardship has fostered.
• A greatly expanded and updated chapter on antivirals guides you through the most recently discovered treatments.
• Comprehensive updates throughout put all of the most current knowledge and techniques in the field at your fingertips.

Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:

• Complete content with enhanced navigation
• A powerful search tool that pulls results from content in the book, your notes, and even the web
• Cross-linked pages, references, and more for easy navigation
• Highlighting tool for easier reference of key content throughout the text
• Ability to take and share notes with friends and colleagues
• Quick-reference tabbing to save your favorite content for future use

About the Author

Daniel Amsterdam
Professor Departments of Microbiology & Immunology, Medicine, and Pathology School of Medicine and Biomedical Sciences State University of New York at Buffalo; Chief of Service, Dept. of Lab

Table of Contents

Preface to the Sixth Edition
Contributing Authors
Perspectives
Daniel Amsterdam and Charles William Stratton

1. The Breakpoint
   Matthew A. Wikler, Franklin R. Cockerill III, and Paul G. Ambrose
2. Antimicrobial Susceptibility on Solid Media
   John D. Turnidge and Jan M. Bell
3. Susceptibility Testing of Antimicrobials in Liquid Media
   Daniel Amsterdam
4. Antimicrobial Susceptibility Testing of Anaerobic Bacteria
   Anilrudh A. Venugopal and David W. Hecht
5. Antimycobacterial Agents: In Vitro Susceptibility Testing and Mechanisms of Action and Resistance
   Clark B. Inderlied and Edward Desmond
6. Antifungal Drugs: Mechanisms of Action, Drug Resistance, Susceptibility Testing, and Assays of Activity in Biological Fluids
   George R. Thompson III and Thomas F. Patterson
7. Antimicrobial Susceptibility Testing for Some Atypical Microorganisms
   Jean-Marc Rolain
8. Applications, Significance of, and Methods for the Measurement of Antimicrobial Concentrations in Human Body Fluids
   Shelly Latte, Emilia Mia Sordillo, and Stephen C. Edberg
9. Molecular Methods for the Detection of Antibacterial Resistance Genes: Rationale and Application
   Kristin Hegstad, Ørjan Samuelsen, Joachim Hegstad, and Arnfinn Sudsfjord
10. Molecular Mechanisms of Action for Antimicrobial Agents: General Principles and Mechanisms for Selected Classes of Antibiotics
    Charles William Stratton
11. Antiviral Agents for HIV, Hepatitis, CMV, and Influenza: Susceptibility Testing Methods, Modes of Action and Resistance
    Daniel Amsterdam
12. Disinfectants and Antiseptics: Modes of Action, Mechanisms of Resistance, and Testing Regimens
    Daniel Amsterdam and Barbara E. Ostrov
13. Evaluation of Antimicrobials in Experimental Animal Infections
    D. A. Andes, Alexander J. Lepak, Niels Frimodt-Møller
14. Extravascular Antimicrobial Distribution and the Respective Blood and Urine Concentrations in Humans
    David M. Bamberger, John Foxworth, Michael Alan Kallenberger, Brian S. Pepito, and Dale N. Gerding

Appendix: Anti-Infective Resistance Resource Guide
Daniel Amsterdam