Basic Physical Pharmacy

Description

Basic Physical Pharmacy provides a thorough yet accessible overview of the principles of physical pharmacy and their application in drug formulation and administration. This definitive guide to physical pharmacy covers all types of pharmaceuticals, from traditional forms and dosages to nanotechnology-based novel dosage design.

Authored by two nationally recognized pharmaceutical scientists and active pharmacy faculty, Basic Physical Pharmacy is clearly organized into four sections: Physical Pharmacy in Solutions; Solid Dosage Forms; Polyphasic Systems; and Drug Delivery and Novel Drug Delivery Systems. Students can build upon their chemistry education to learn the physicochemical properties of drugs and their therapeutic effects on the body. With a highly accessible approach, Basic Physical Pharmacy will help students comprehend and apply the principles of physical pharmacy in clinical practice.

Covers major drug products and delivery systems

Features current trends in pharmaceutical research and development, including nanotechnology-based dosage design

Includes many examples of useful equations and formulation methods

Contains over 200 illustrations, photos, and tables

Topics Include:

• Solutions
• Ionization of Drugs in Solutions
• Buffers and Buffered Solutions
• Drug Solubility
• Diffusion and Dissolution
• Distribution Phenomena
• Complexation and Protein Binding
• Interfacial Phenomena
• Rheology
• Colloids
• Suspensions and Emulsions
• Semisolid Dosage Forms Dermatologicals
• Suppositories
• Powders
• Capsules
• Tablets
• Aerosols
• Sterile Dosage Forms
• Ophthalmic Formulations
• Radiopharmaceuticals
• Modified Release Drug Delivery Systems
• Biotechnology Products
• Drug Product Stability

Table of contents

Section I Physical Pharmacy in Solutions
Chapter 1 Molecular expressions and Electrolyte Properties of Drug Molecules
Chapter 2 Colligative Properties and Isotonic Solutions
Chapter 3 Acid-Base Equilibrium and Buffered Solutions
Chapter 4 Drug Solubility and Distribution in Immiscible Systems
Chapter 5 Molecular Interactions of Drugs in Pharmaceutical and biological Systems
Chapter 6 Chemical Kinetics: Principles and Applications

Section II Pharmaceutical Development I: Solid Dosage Forms
Chapter 7 Drug Absorption, Bioavailability and Dosage Forms: A Regulatory Perspective
Chapter 8 Diffusion, Dissolution, and Permeability
Chapter 9 Pharmaceutical Powders
Chapter 10 Tablets and Capsules

Section III Pharmaceutical Development II: Polyphasic Systems
Chapter 11 Interfacial Phenomena
Chapter 12 Rheology in Pharmacy
Chapter 13 Colloids, Suspensions, and Emulsions
Chapter 14 Transdermal Drug Delivery

Section IV Current Concept and Novel Drug Delivery Systems
Chapter 15 Advanced Drug Delivery Systems
Chapter 16 Parenteral Drug Delivery System
Chapter 17 Delivery of Biotechnology Products
Chapter 18 Application of Nanosciences in Pharmaceutics