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Quality of Life: The Assessment, Analysis and Reporting of Patient-Reported Outcomes
Fayers, P. — Machin, D.
3ª Edición Enero 2016
Inglés
Tapa dura
656 pags
1238 gr
18 x 25 x 3 cm
ISBN 9781444337952
Editorial WILEY
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Description
The assessment of patient reported outcomes and health-related quality of life
continue to be rapidly evolving areas of research and this new edition reflects
the development within the field from an emerging subject to one that is an
essential part of the assessment of clinical trials and other clinical studies.
This book is aimed at everyone involved in quality-of-life research and is applicable
to medical and non-medical, statistical and non-statistical readers. It is of
particular relevance for clinical and biomedical researchers within both the
pharmaceutical industry and clinical
practice.
The analysis and interpretation of quality-of-life assessments relies on a variety
of psychometric and statistical methods which are explained in this book in
a non-technical way. The result is a practical guide that covers a wide range
of methods and emphasizes the use of simple techniques that are illustrated
with numerous examples, with extensive chapters covering qualitative and quantitative
methods and the impact of guidelines. The material in this new third edition
reflects current teaching methods and content widened to address continuing
developments in item response theory, computer adaptive testing, analyses with
missing data, analysis of ordinal data, systematic reviews and meta-analysis.
Contents
Preface to the third edition
Preface to the second edition
Preface to the first edition
List of Abbreviations
Part One: Developing and validating instruments for assessing Quality of Life
and Patient-Reported Outcomes.
1 Introduction
2 Principles of measurement scales
3 Developing a questionnaire
4 Scores and measurement: validity, reliability, sensibility
5 Multi-item scales
6 Factor analysis and structural equation modeling
7 Item response theory and differential item functioning
8 Item banks, item linking and computer-adaptive tests
Part 2: Assessing, analysing and reporting Patient-Reported Outcomes and the
Quality of Life of patients.
9 Choosing and scoring questionnaires
10 Clinical trials
11 Samples sizes
12 Cross-sectional analysis
13 Exploring longitudinal data
14 Modelling longitudinal data
15 Missing data
16 Practical and reporting issues
17 Death and Quality-adjusted survival
18 Clinical interpretation
19 Biased reporting and response shift
20 Meta-analysis
Appendix – Examples of Instruments
Appendix – Statistical tables
Appendix – References
Index
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