This book builds on the success of previous editions, once again providing hepatologists the most current clinical guide on how to best treat the liver transplant recipient. With an international mix of experienced contributors, this new edition highlights initial indication and selection of the potential recipient, management of the donor organ, post-operative complications in the patient through to acute recovery, long-term follow-up, and continued health. This provides the user a complete guide to the correct clinical management of both the recipient and the donor organ through all stages of transplantation.
Table of Contents
- List of Contributors.
Part 1: Management of the Potential Transplant Recipient.
1. Selection and Evaluation of the Recipient (including retransplantation) (Audrey Coilly and Didier Samuel).
2. Monitoring the Patient Awaiting Transplantation (Andreas Geier and Beat Müllhaupt).
3. Management of Portal Hypertension (Juan Carlos Garcia-Pagan, Juan G. Abraldes and Jaime Bosch).
4. Management of Renal Disease in the Liver Transplant Candidate (Andrés Cárdenas and Pere Ginès).
5. Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension (Victor I. Machicao and Michael B. Fallon).
6. Psychiatric and Substance Abuse Evaluation of the Potential Liver Transplant Recipient (Thomas P. Beresford).
7. Organ Allocation in Liver Transplantation: Ethics, Organ Supply, and Evidence Based Practice (Nicole Siparsky, David Axelrod and Richard B. Freeman).
8. Viral Hepatitis and Transplantation (Geoffrey W. McCaughan).
9. Metabolic Liver Diseases (Maureen M.J. Guichelaar and Michael R. Charlton).
10. Cholestatic and Autoimmune Liver Disease (Ulrich Beuers).
11. Hepatocellular Carcinoma (Maria Reig, Alejandro Forner and Jordi Bruix).
12. Cholangiocarcinoma (Howard C. Masuoka, Gregory J. Gores, Charles B. Rosen).
13. Rare Indications for Liver Transplantation (Stevan A. Gonzalez).
14. HIV Patients (Marion G. Peters and Peter G. Stock). 15. Living Donor Liver Transplantation (Robert S. Brown, Jr.).
16. Fulminant Hepatic Failure (Michael A. Heneghan and William Bernal).
Part 2: Donor Issues and Management in the Perioperative Period.
17. Extended Criteria Donor (Ashraf Mohammad El-Badry, Mickael Lesurtel).
18. Liver Transplantation Using Donors after Cardiac Death (Paolo Muiesan, Laura Tariciotti, Chiara Rocha).
19. Transmission of Malignancies and Infection through Donor Organs (Aaron M. Winnick and Lewis Teperman).
20. The Transplant Operation (Christian Oberkofler, Olivier de Rougemont and Philipp Dutkowski).
21. The Difficult Surgical Patients (Philipp Dutkowski, Stefan Breitenstein and Pierre-Alain Clavien).
22. Domino and Split Transplantation (Abhideep Chaudhary and Abhinav Humar).
23. Surgical Aspects of Living Donor Transplantation (Kelvin K.C. Ng and Sheung Tat Fan).
24. Anesthesia (Beatrice Beck-Schimmer).
25. Coagulation and Blood Transfusion Management (Herman G. D. Hendriks, Ton Lisman, Robert J. Porte).
26. Critical Care of the Liver Transplant Recipient (Markus Béchir, Erik Schadde, Philipp Dutkowski).
27. Rejection and Immunosuppression Trends in Liver Transplantation (James F. Trotter).
28. Vascular Complications after Liver Transplantation (Srinath Chinnakotla and Goran Klintmalm).
29. Biliary Complications Following Liver Transplantation (Sanna op den Dries, Robert C. Verdonk, Robert J. Porte).
30. The Role of Histopathology (Achim Weber).
Part 3: Chronic Problems in the Transplant Recipient.
31. Medical Problems after Liver Transplantation (Eberhard L. Renner and Marco Puglia).
32. Prevention and Treatment of Recurrent HBV and HCV Infection (Ed Gane).
33. Recurrence of the Original Disease (James Neuberger).
34. Infections in the Organ Transplant Recipient (Nicolas J. Mueller and Jay A. Fishman).
35. Cutaneous Diseases in Liver Transplant Recipients (Sylvie Euvrard and Jean Kanitakis).
36. Post Transplant Lymphoproliferative Disorder and Other Malignancies after Liver Transplantation (Natasha Chandok and Kymberly D.S. Watt).
37. Sexual function and fertility after liver transplantation (Andreas Geier and Beat Müllhaupt).
Part 4: Pediatric Liver Transplantation.
38. Special Considerations in Pediatric Liver Transplantation (Brandy Ries Lu and Ronald J. Sokol).
Pierre-Alain Clavien, MD, PhD, FACS, FRCS (Eng), FRCS (Ed), Professor and Chairman, Department of Surgery. Head, Division of Visceral & Transplantation Surgery, University Hospital Zurich, Switzerland
Professor Clavien is a world-wide renowned surgeon-scientist, currently professor and chairman of the Department of Surgery in Zurich, Switzerland. His areas of research include organ preservation, liver ischemia-reperfusion injury and regeneration, and pathogenesis of cancer, as well as outcome research. He received many competitive grants and awards, including one of the most prestigious prices for scientific research, the Otto Naegeli Award.
Dr James Trotter is the Medical Director of Liver Transplantation at Baylor University Medical Center at Dallas. Dr. Trotter's primary interests include end-stage liver disease and the management of liver transplant candidates and recipients. Dr. Trotter specializes in hepatitis C, ascites, complications of portal hypertension, including esophageal varices and hepatic encephalopathy. He also has vast experience in the management of medical complications after liver transplantation including immunosuppression in liver transplant recipients and the treatment of hepatitis C before and after liver transplantation.