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Obesity before Birth. Maternal and Prenatal Influences on the Offspring
Lustig, R.
1ª Edición Octubre 2010
Inglés
Tapa dura
415 pags
1200 gr
16 x 24 x 3 cm
ISBN 9781441970336
Editorial SPRINGER
LIBRO IMPRESO
-5%
207,99 €197,59 €IVA incluido
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Recíbelo en un plazo de
2 - 3 semanas
About this book
Obesity obeys the First Law of Thermodynamics. The routine assumption is that
obesity is the result of a mismatch between calories in and calories out; in
other words, the result of two divergent behaviors. However, there is mounting
evidence that biochemical forces can drive obligate weight gain, and that the
observed behaviors of increased energy intake and decreased energy expenditure
are secondary to these processes. Furthermore, many of these biochemical forces
are determined in utero; resulting in a developmental drive toward obesity and
disease in later life. Four distinct prenatal forces have thus far been identified:
1) genetics; 2) epigenetics; 3) developmental programming; and 4) environmental
obesogens. This volume explores the evidence for each of these in detail in
human and animal models, and attempts to provide a cohesive analysis of the
biochemical bases of obesity. This volume will appeal to geneticists, developmental
biologists, endocrinologists, epidemiologists, toxicologists, obstetrician/gynecologists,
nutritionists, veterinary scientists, animal husbandry researchers, domestic
species researchers, and obesity researchers and practitioners. "This very
timely volume provides an in-depth scholarly overview of a critical challenge
facing our society—the obesity epidemic. Dr. Robert H. Lustig has assembled
expert authors to address the fundamental contribution of preprogrammed genetic
disorders leading to obesity, as well as the role of very early environmental
influences. The chapters range from classic genetic mechanistic understanding
through intra-uterine epigenetic influences, factors determining developmental
programming, and the new clinical science of perinatal obesogens. Obesity Before
Birth: Maternal and prenatal influences on the offspring, brings easily accessible,
cutting edge information to geneticists, pediatricians, endocrinologists, as
well as those clinicians and scientists pursuing the complex yet elusive causes
of childhood obesity and related disorders." - Shlomo Melmed, M.D. Series
Editor
Content Level » Professional/practitioner
Keywords » GNAS locus - Obesity - Prader-Willi Syndrome - clinical obesity
- obesity risk
Related subjects » Food Science & Nutrition - Human Genetics - Internal
Medicine
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