Pharmaceutical Process Engineering

A guide to basic engineering principles, practical aspects of drug production, and development processes for converting bulk pharmaceutical products into patient-ready dosage forms.

Topics:

• the increased usage of computer aided design, set to become a standard procedure
• quality principles, including: quality by design; mathematical/statistical approaches to experimental design; computer aided design; and PAT (process analytical technology)
• heat transfer, mass transfer, and fluid flow
• global/local manufacturing environments
• preparing sterile materials for injection
• drying, evaporation, and crystallization processes for concentrated drug solutions/solids
• filtration/centrifugation for collecting/removing drug particles
• particle size reduction, mixing, granulation, and drying methods for capsule and tablet
• manufacturing biological materials