Tissue and Cell Processing. an Essential Guide

Description

By presenting the latest technological advances and growing national and international regulation, this new book explores state-of-the-art developments in the challenging field of tissue and cell processing. It provides a guide to easier and safer practice in operational principles of preservation, decontamination, and sterilization. Nearly half of the book is devoted completely to tissue- or cell-specific issues relating to processing. With lists of learning points and case studies which consist of sample processing protocols, descriptions of where processing went wrong, sample risk assessments, or validation studies, the authors help you find specific information fast.

Table of Contents

• List of Contributors
• Foreword
• Preface

1. Regulations and Standards
   Michael Cox and Scott A. Brubaker
2. Risk management in Tissue & Cell Processing
   Diane Wilson and Johann Kurz
3. Principles of Cell Collection and Tissue Recovery
   Helen Gillan, Derwood Pamphilon, Scott A. Brubaker
4. Principles of Cell and Tissue Cryopreservation
   Ying C. Song and David E. Pegg
5. Principles of tissue decontamination and sterilization
   Lloyd Wolfinbarger, Jr. and Pierre Lory
6. Control of Contamination and Cross Contamination During Processing: Optimising the Processing Environment
   Lisa Nair, Marisa Roma Herson and Kyle Bennett
7. The Principles of Process Validation and Equipment Qualification
   Martell Winters and Richard Lomas
8. Biomechanical and Biocompatibility Testing Considerations
   Caroline A Hartill
9. Coding and Traceability
   Stefan Poniatowski, Izabela Uhrynowska-Tyszkiewicz and Ineke Slaper-Cortenbach
10. Training of Tissue Bank Personnel
    Martí Manyalich, Debbie Butler Newman, Jacinto Sánchez Ibáñez, Aurora Navarro, Gloria Páez, & Aziz Nather
11. Cardiac Tissue: Specific Recovery and Processing Issues
    Alyce Linthurst Jones, Robert Parker, Linda Manning and Helmi Albrecht
12. Skin: specific recovery and processing issues
    Elisa Pianigiani and Jan L. Pierce
13. Ophthalmic tissues: recovery and processing issues
    Diego Ponzin, Patricia Dahl and Elisabeth Pels
14. Skeletal Tissue: Specific Recovery and Processing Issues
    Joel Osborne, Art Kurz, Esteve Trias and Oscar Fariñas
15. Processing of cells for transplantation
    Mark W Lowdell & Edward Samuel
16. Gametes and embryos: specific collection and processing issues
    Montserrat Boada and Anna Veiga
17. Engineering of human tissue grafts
    John N. Kearney and Francisco da Costa

Author Information

Deirdre Fehily PhD
Inspector and Technical Advisor, Tissues and Cells, National Transplant Centre, Rome, Italy

Scott A. Brubaker CTBS
Chief Policy Officer, American Association of Tissue Banks, McLean, Virginia, USA

John N. Kearney BSc, PhD, CBiol, MIBiol, SRCS
Head of Tissue Services/Lead Scientist/PI for Research, Liverpool Blood Centre, NHS Blood & Transplant, Liverpool, UK

Lloyd Wolfinbarger Jr. PhD
BioScience Consultants, llc, Norfolk, Virginia, USA