This second edition consists of more than 1,800 pages contained within 98 chapters.
The price includes a fully searchable companion CD ROM with the complete text and over 300 images from the book in full colour.
VOLUME 1. The Scientific Basis of Allergy.
Part 1 Immunology of the Allergic Response.
1 Allergy and Hypersensitivity: History and Concepts
2 Development of Allergy and Atopy
3 T Cells and Cytokines in Asthma and Allergic Inflammation
4 Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma
5 IgE and IgE Receptors
6 Immunoglobulin Gene Organization and Expression and Regulation of IgE
7 Environmental Factors in IgE Production
8 Antigen-presenting Dendritic Cells and Macrophages
9 Innate Immunity in Allergic Disease
10 Signal Transduction in Allergic and Inflammatory Cells
Part 2 Inflammatory Cells and Mediators.
11 Mast Cells: Biological Properties and Role in Health and Allergic Diseases
12 Eosinophils: Biological Properties and Role in Health and Disease
13 Neutrophils: Biological Properties and Role in Health and Allergic Diseases
14 Basophils: Biological Properties and Role in Allergic Diseases
15 Leukocyte Adhesion in Allergic Inflammation
16 Airway Epithelium
17 Airway Vascularity in Asthma.
18 Fibroblasts and the Extracellular Matrix
19 Immune Complexes and Complement: Their Role in Host Defense and in Disease
20 Bradykinin Pathways and Allergic Disease
24 Late-phase Allergic Reactions in Humans
Part 3 Pharmacology.
26 Lipid Mediators: Leukotrienes, Prostanoids, Lipoxins, and Platelet-activating Factor
27 Theophylline and Isoenzyme-selective Phosphodiesterase Inhibitors.
28 Adrenergic Agonists and Antagonists
29 Cholinergic Antagonists
30 Antileukotriene Agents
32 Immunomodulating Drugs
Part 4 Physiology.
33 Physiologic Aspects of Asthma
34 Aerosol Delivery Systems
35 Bronchial Hyperresponsiveness
36 Exercise-induced Bronchoconstriction: Animal Models
37 Exercise-induced Bronchoconstriction: Human Models
38 Sensory and Autonomic Nervous System in Asthma and Rhinitis
39 Mucus and Mucociliary Clearance in Asthma and Allergic Rhinitis.
40 Biology of Vascular Permeability
41 Airway Smooth Muscle
Part 5 Allergens.
42 Biochemistry of Allergens and Recombinant Allergens
43 Host Responses to Allergens
44 Allergen Extracts and Standardization
45 Grass, Tree, and Weed Pollen
46 Fungi as Allergens
47 Dust Mites and Asthma
48 Animal Allergens
49 Airborne Allergens and Irritants in the Workplace
50 Allergens from Stinging Insects: Ants, Bees, and Vespids
51 Cockroach Allergens, Environmental Exposure, and Asthma
52 Food Allergens
53 Latex Allergy
Part 6 Animal Models of Asthma.
54 Primate Models of Allergic Asthma
55 Airway Remodeling in Small Animal Models
56 Are Animal Models of Asthma Useful?
VOLUME 2. Allergic Diseases: Etiology, Diagnosis and Treatment.
Part 7 Etiology and Pathology.
57 Genetics of Asthma and Atopic Dermatitis
58 Epidemiology of Asthma, Atopy, and Atopic Disease
59 The Allergy March
60 Outdoor Air Pollution and Allergic Airway Disease
61 Indoor Air Pollution
62 Molecular Immunopathology of Allergic Disease
Part 8 Diagnosis of Allergic Disease.
63 Principles and Practice of Diagnosis and Treatment of Allergic Disease
64 Skin Testing in Diagnosis and Management of Respiratory Allergic Diseases
65 Allergy Testing in the Laboratory
66 Measurement of Markers of Inflammation in Induced Sputum and Exhaled Air
Part 9 Allergic Rhinoconjunctivitis and Immunotherapy.
67 Definition and Classification of Allergic Rhinitis and Upper Airways Diseases
68 Pathophysiology of Allergic Rhinitis
69 Management and Treatment of Allergic Rhinitis
70 Nasal Polyps and Rhinosinusitis
71 Ocular Allergy
72 Mechanisms in Allergen Injection Immunotherapy.
73 Allergen Injection Immunotherapy: Indications and Practice
74 Sublingual Immunotherapy
75 Novel Approaches to Allergen Immunotherapy
Part 10 Asthma and its Treatment.
76 Definition, Clinical Features, Investigations, and Differential Diagnosis
77 Asthma in Infancy and Childhood
78 Pathogenesis of Asthma
79 Pathology of Asthma
80 Management of Chronic Asthma
81 Anti-IgE in Persistent Severe Allergic Asthma
82 Occupational Asthma
83 New Drugs for the Treatment of Allergy and Asthma
Part 11 Eosinophil-associated Disease and Hypersensitivity Pneumonitis.
84 Allergic Bronchopulmonary Aspergillosis
85 Extrinsic Allergic Alveolitis/Hypersensitivity Pneumonitis
86 Pulmonary Eosinophilia
87 Hypereosinophilic Syndromes
Part 12 Allergy and the Skin.
88 Atopic Dermatitis
89 Contact Dermatitis
90 Urticaria and Angioedema
Part 13 Anaphylaxis and Allergy to Food and Drugs.
93 Food Allergy and Eosinophilic Gastroenteropathies
94 Drug Hypersensitivity
95 Hypersensitivity to Aspirin and other NSAIDs
96 Insect Sting Allergy: Ulrich R. Müller
Part 14 Prevention of Allergic Disease.
97 Prevention of Allergic Disease
98 Prevalence of Atopic Disorders in a Developing World: Pitfalls and Opportunities