Handbook on Hyperbaric Medicine

It is now ten years since the first Handbook on Hyperbaric Medicine was published. During this time there have been many major advances: our understanding of the actions of hyperbaric oxygenation has been elucidated by several studies; clinical practice is becoming more scientific; various consensus-derived organisational and operational recommendations and guidelines are now widely accepted.

As for Europe, these positive developments are largely due to the continuous action of the European Committee for Hyperbaric Medicine (ECHM). One of the most successful initiatives was the start of a specific European research action sponsored by the EU Co-operation in Science and Technology (COST) programme. The specific COST Action for hyperbaric medicine, COST B14, has been completed and has provided the impetus for the publication of this new Handbook.

This book is a reference document for researchers and clinicians, and is also of excellent use for both teachers and students.

Table of contents

Foreword D. Mathieu Contributors Preface D. Bakker A History of Hyperbaric Medicine F. Wattel

Part I Physical and Pathophysiological Bases of Hyperbaric Oxygen Therapy.
Editors: B. Ratzenhofer, J. Niinikoski, M. Hamilton-Farell
1.1. Physics of Hyperbaric Pressure W. Weslau 1.2. Biochemistry of Oxygen A. Courtiere 1.3. Physiologic Effects of Increased Barometric Pressure W. Weslau 1.4. Physiologic Effects of Hyperbaric Oxygen on Oxygen Transport and Tissue Oxygen Pressure B. Ratzenhofer-Komenda, R. Favory, W. Weslau, F.M. Smolle-Jüttner, D. Mathieu 1.5. Physiologic Effects of Hyperbaric Oxygen on Hemodynamics and Microcirculation D. Mathieu, R. Favory, F. Collet, J.C. Linke, F. Wattel 1.6. Physiologic Effects of Hyperbaric Oxygen on Microorganisms and Host Defences Against Infection D. Mathieu, F. Wattel 1.7 Physiologic Effects of Hyperbaric Oxygen on Ischemia Reperfusion Phenomenon S. Van Poucke, P. Jorens, L. Beaucourt 1.8 Physiologic Effects of Hyperbaric Oxygen on Wound Healing Processes J. Niinikoski 1.9 Physiologic Effects of Hyperbaric Oxygen on DNA and DNA Repair C. Muth, M. Gröger, P. Radermacher, G. Speit

Part II: Indications for HBO.
Editors: D. Mathieu, J. Schmutz, F. Cronje
2.1 Methodology for Assessing Hyperbaric Oxygen Therapy in Clinical Practice F. Wattel, D. Mathieu 2.2 Recommended Indications 2.2.1 Dysbaric Illness A. Marroni, F. Cronje, J. Meintjes, R. Cali-Corleo 2.2.2 Gas Embolism D. Mathieu, S. Tissier, M. Boulo 2.2.3 Carbon Monoxide Poisoning D. Mathieu, M. Mathieu-Nolf, J.C. Linke, R. Favory, F. Wattel 2.2.4 Necrotizing Soft Tissue Infections D. Mathieu, R. Favory, J.F. Cesari, F. Wattel. 2.5 Intra-Cranial Abscess L. Lampl, G. Frey 2.2.6 Crush Injury and Other Acute Traumatic Ischemia A. Kemmer 2.2.7 Compromised Skin Graft and Flap T. Mesimeris 2.2.8 Radio-Induced Lesion in Normal Tissues D. Pasquier, J. Schmutz, E. Lartigau 2.2.9 Non-Healing Wounds D. Mathieu, J.C. Linke, F. Wattel 2.2.10 Persistent Osteomyelitis A. Kemmer, T. Stein, C. Hierholzer 2.2.11 Sudden Deafness A. Barthelemy, M. Rocco 2.2.12 Neuroblastoma A. van der Kleij, P. Sminia 2.3 Optional Indications 2.3.1 Burns P. Germonpré 2.3.2 Anoxic Encephalopathy F. Wattel 2.3.3 Pleuropulmonary Anaerobic Infections D. Mathieu 2.3.4 Post Vascular Procedure Reperfusion Syndrome and Limb Replantation J. Schmutz 2.3.5 Acute Ischemic Ophtalmological Disorders A. Weinberger, U. Siekmann 2.3.6 Pneumatosis Cystoides Intestinalis J. Niinikoski 2.4 Controversial and Non Indications 2.4.1 Femoral Head Necrosis L. Ditri, M. Montanari,Y. Melamed, D. Reis 2.4.2 Cerebrovascular Incidents (Stroke) F. Cronje, W. Duim, A. Marroni, R. Cali-Corleo 2.4.3 Post-Sternotomy Mediastinitis A. Barthelemy 2.4.4 Sickle Cell Disease H. Medhaoui 2.4.5 Brain Injury and Spinal Cord Injury J. Schmutz 2.4.6 Myocardial Infarction J. Schmutz 2.4.7 Malignant Otitis Externa J. Schmutz 2.4.8 Other Controversial or Non Indications J. Schmutz

Part III: Practice of hyperbaric medicine.
Editors: J. Kot, A. Kemmer, P. Germonpré
3.1. Hyperbaric Chamber and Equipment J. Kot, R. Houman,P. Müller 3.2. Organisation of a Hyperbaric Center J. Kot, Z. Sicko 3.3. Patient Management A. Kemmer, C. Muth, D. Mathieu 3.4. A Cost-Effectiveness Evaluation of Hyperbaric Oxygen Therapy A. Marroni, P. Longobardi, R. Cali-Corleo 3.5. Education and Training of Hyperbaric Centre Personal J. Desola 3.6. Safety in Hyperbaric Medicine J. Kot, R. Houman, R. Gough-Allen 3.7. Complications of Hyperbaric Oxygen Therapy 3.7.1 Barotraumatism F. Roque, A. Simão 3.7.2 Oxygen Toxicity N. Bitterman, H. Bitterman 3.8. Organisation of Hyperbaric Medicine in Europe D. Bakker, A. Marroni, D. Mathieu 3.9. Research in Hyperbaric Medicine P. Germonpré, D. Mathieu
Annex List of Hyperbaric Therapeutic Centres in Europe P. Germonpré, J. Kot Index.