Placental and Gestational Pathology (Diagnostic Pediatric Pathology)

Part I. Introduction:
1. Normal development
Part II. Early Pregnancy Pathology:
2. Early pregnancy loss with normal karyotype
3. Early pregnancy loss with abnormal karyotype
4. Gestational trophoblastic disease
Part III. Maternal Uteroplacental-Vascular Pathology:
5. Maternal vascular/trophoblastic developmental abnormalities
6. Distal villous hypoplasia, focal and diffuse
7. Maternal vascular malperfusion
8. Loss of maternal vascular integrity
Part IV. Fetal Stromal-Vascular Pathology:
9. Fetal-stromal vascular developmental abnormalities
10. Fetal vascular malperfusion
11. Loss of fetal vascular integrity
Part V. Inflammatory Processes:
12. Placental infections
13. Chronic villitis/ villitis of unknown etiology
14. Chronic inflammatory lesions sometimes associated with villitis of unknown etiology (Vue)
15. Chronic histiocytic intervillositis
Part VI. Other Pathologic Processes:
16. Placental size, shape, and umbilical cord abnormalities
17. Perivillous fibrin deposition
18. Atypical intraplacental hemorrhages/ thrombi
19. Meconium effects
20. Increased circulating fetal nucleated red blood cells
21. Early and late membrane/amnion rupture and amnion nodosum
22. Metastatic tumors
23. Heterotopias and germ cell tumors
24. Lysosomal storage disease, Bartter syndrome, and mimics
Part VII. Pathology of Multiple Gestations:
25. The pathology of monochorionic placentation
26. Dichorionic or higher order multiple gestations
Part VIII. Uteroplacental Pathology:
27. Abnormal placental location
28. Morbidly adherent placenta
29. Uterine rupture/ dehiscence
30. Postpartum hemorrhage
Part IX. Clinicopathologic Correlations: Placental Pathology and Adverse Pregnancy Outcomes:
31. Spontaneous preterm delivery (premature labor, premature rupture of membranes, vaginal bleeding, cervical insufficiency)
32. Fetal growth restriction
33. Fetal death
34. Central nervous system injury
35. Recurrent pregnancy loss

This concise and comprehensive resource is vital for the pathologist faced with providing accurate, timely, and clinically useful diagnoses for placentas, products of conception, and gravid hysterectomies. Combining the pathologic, research, and clinical expertise of a diverse group of editors and authors from centers of excellence for placental pathology, this book enables easy application of the latest Amsterdam international consensus classification criteria, with cross-references to previous terminology and a pathophysiology-based classification system. It provides complete descriptions and illustrations of diagnostic gross, microscopic, and immunohistochemical findings together with a thorough discussion of potential pitfalls and differential diagnosis. Current theories of the genetic and physiologic basis for disease processes, culminating in placental lesions are discussed. The book features high-quality images and standardized measurement tables to assist real-time diagnoses and provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.

Raymond W. Redline, Case Western Reserve University, Ohio
Raymond W. Redline is Professor of Pathology and Reproductive Biology at University Hospitals Cleveland Medical Center, where he currently directs the Pediatric, Perinatal, and Gynecologic Pathology sections. He has served for 32 years on the faculty of Harvard Medical School and Case Western Reserve University, Ohio, and chaired the Society for Pediatric Pathology Placenta Nosology Project.

Theonia K. Boyd, Harvard Medical School, Boston
Theonia K. Boyd is Associate Professor of Pathology and Director of Anatomic Pathology at Boston Children's Hospital, and a staff member of the Division of Women's and Perinatal Pathology at Brigham and Women's Hospital. She served on the faculty of Tufts University School of Medicine and then Harvard Medical School, Boston, for a total of 22 years.

Drucilla J. Roberts, Harvard Medical School, Boston
Drucilla J. Roberts is Associate Professor of Pathology at Harvard Medical School and Associate Pathologist at Massachusetts General Hospital. She previously held a fellowship in Women's and Perinatal Pathology and a post-doctoral fellowship in the Department of Genetics at Harvard Medical School, Boston. Along with Dr Boyd, she is co-Director of a CME course on Placental Pathology.