Lewin's Genes XII (Includes Navigate 2 Advantage Access)

Description

Molecular Biology. It's All Here.

Each new print copy includes Navigate 2 Advantage Access that unlocks a comprehensive and interactive eBook with engaging animations, student practice activities and assessments, a full suite of instructor resources, and learning analytics reporting tools.

Long considered the quintessential molecular biology textbook, for decades Lewin's GENES has provided the most modern presentation to this transformative and dynamic science. Now in its twelfth edition, this classic text continues to lead with new information and cutting-edge developments, covering gene structure, sequencing, organization, and expression. Leading scientists provide revisions and updates in their respective areas of study offering readers current research and relevant information on the rapidly changing subjects in molecular biology. No other text offers a broader understanding of this exciting and vital science or does so with higher quality art and illustrations. Lewin's GENES XII continues to be the clear choice for molecular biology and genetics.

With Navigate 2, technology and content combine to expand the reach of your classroom. Whether you teach an online, hybrid, or traditional classroom-based course, Navigate 2 delivers unbeatable value.

Features & Benefits

• Praised for its organization and comprehensiveness, Lewin's GENES XII covers nearly every aspect of molecular biology and genetics
• NEW - contains expanded coverage of epigenetics and additional research studies and data
• Revised art program offers a stunning interior design with many new figures, some reflecting new developments in the field, particularly in the topics of chromatin structure and function, epigenetics, and regulation by noncoding and microRNAs in eukaryotes
• High-quality illustrations and photographs engage readers and unlock complex topics and molecular processes

Applicable Courses

Written for the upper-division undergraduate or graduate Molecular Biology and Molecular Genetics courses, offered at the college and university level, within the departments of biology, molecular & cellular biology, and biochemistry.

Contents

Part  1  Genes and Chromosomes
Chapter  1  Genes Are DNA and Encode RNAs and Polypeptides
Chapter  2  Methods in Molecular Biology and Genetic Engineering
Chapter  3  The Interrupted Gene
Chapter  4  The Content of the Genome
Chapter  5  Genome Sequences and Evolution
Chapter  6  Clusters and Repeats
Chapter  7  Chromosomes
Chapter  8  Chromatin

Part  2  DNA Replication and Recombination
Chapter  9  Replication Is Connected to the Cell Cycle
Chapter  10  The Replicon: Initiation of Replication
Chapter  11  DNA Replication
Chapter  12  Extrachromosomal Replicons
Chapter  13  Homologous and Site-Specific Recombination
Chapter  14  Repair Systems
Chapter  15  Transposable Elements and Retroviruses
Chapter  16  Somatic DNA Recombination and Hypermutation in the Immune System

Part  3  Transcription and Posttranscriptional Mechanisms
Chapter  17  Prokaryotic Transcription
Chapter  18  Eukaryotic Transcription
Chapter  19  RNA Splicing and Processing
Chapter  20  mRNA Stability and Localization
Chapter  21  Catalytic RNA
Chapter  22  Translation
Chapter  23  Using the Genetic Code

Part  4  Gene Regulation
Chapter  24  The Operon
Chapter  25  Phage Strategies
Chapter  26  Eukaryotic Transcription Regulation
Chapter  27  Epigenetics I
Chapter  28  Epigenetics II
Chapter  29  Noncoding RNA
Chapter  30  Regulatory RNA

Authors

Jocelyn E. Krebs, PhD-Professor, University of Alaska, Anchorage

Jocelyn E. Krebs has been a member of the Department of Biological Sciences at the University of Alaska Anchorage since 2000. She received her B.A. in Biological Sciences from Bard College in 1991 and her PhD in Molecular and Cell Biology from the University of California Berkeley in 1997. Her research focuses on the mechanisms by which DNA transactions such as transcription and repair are accomplished in the context of chromatin. Her teaching interests are in Molecular Biology (taught at the undergraduate, graduate, and first-year medical school levels), as well as the Molecular Biology of Cancer.

Elliott S. Goldstein, PhD-Associate Professor, Arizona State University

Elliott S. Goldstein earned his B.S. in Biology from the University of Hartford (Connecticut) and his Ph.D. in Genetics from the University of Minnesota, Department of Genetics and Cell Biology. Following this, he was awarded an N.I.H. Postdoctoral Fellowship to work with Dr. Sheldon Penman at the Massachusetts Institute of Technology. Leaving Boston, he joined the faculty at Arizona State University in Tempe, where he is an Associate Professor in the Cellular, Molecular and Biosciences program in the School of Life Sciences, and in the Honors Disciplinary Program. His research interests are in the area of molecular and developmental genetics of early embryogenesis in Drosophila melanogaster. In recent years, he has focused on the Drosophila counterparts of the human proto-oncogenes jun and fos. His primary teaching responsibilities are in the undergraduate General Genetics course as well as the graduate level Molecular Genetics course. 

Stephen T. Kilpatrick, PhD-Associate Professor, University of Pittsburgh at Johnstown

Stephen T. Kilpatrick is an Associate Professor of Biology at the University of Pittsburgh at Johnstown (UPJ). He received a B.S.  in Biology for Eastern College (now Eastern University) and a PhD from the Program in Ecology and Evolutionary Biology at Brown University. His research an teaching interests are in evolutionary molecular genetics. UPJ is an undergraduate degree-granting campus of the University of Pittsburgh, and Dr. Kilpatrick regularly teaches undergraduate courses in majors introductory biology, genetics, evolution, molecular genetics, and biostatistics. Prior to coauthoring the Second Edition of Lewin's Essential Genes, Dr. Kilpatrick has co-authored the test banks for the first edition and for Lewin's GENES VIII and GENES IX. He has also authored ancillaries and pedagogical materials for several introductory non-majors and majors biology and genetics textbooks.