Harrison's Manual of Medicine

Contributors

Preface

Acknowledgments

SECTION 1 Care of the Hospitalized Patient

1 Electrolytes

2 Acid-Base Disorders

3 Diagnostic Imaging in Internal Medicine

4 Procedures Commonly Performed by Internists

5 Principles of Critical Care Medicine

6 Pain and Its Management

7 Assessment of Nutritional Status

8 Enteral and Parenteral Nutrition

9 Transfusion and Pheresis Therapy

10 Palliative and End-of-Life Care

SECTION 2 Medical Emergencies

11 Cardiovascular Collapse and Sudden Death

12 Shock

13 Narcotic Overdose

14 Sepsis and Septic Shock

15 Acute Pulmonary Edema

16 Acute Respiratory Distress Syndrome

17 Respiratory Failure

18 Confusion, Stupor, and Coma

19 Stroke

20 Subarachnoid Hemorrhage

21 Increased Intracranial Pressure and Head Trauma

22 Spinal Cord Compression

23 Hypoxic-Ischemic Encephalopathy

24 Status Epilepticus

25 Diabetic Ketoacidosis and Hyperosmolar Coma

26 Hypoglycemia

27 Oncologic Emergencies

28 Anaphylaxis

29 Bites, Venoms, Stings, and Marine Poisonings

SECTION 3 Common Patient Presentations

30 Fever, Hyperthermia, and Rash

31 Generalized Fatigue

32 Unintentional Weight Loss

33 Chest Pain

34 Palpitations

35 Dyspnea

36 Cyanosis

37 Cough and Hemoptysis

38 Edema

39 Abdominal Pain

40 Nausea, Vomiting, and Indigestion

41 Dysphagia

42 Diarrhea, Malabsorption, and Constipation

43 Gastrointestinal Bleeding

44 Jaundice and Evaluation of Liver Function

45 Ascites

46 Lymphadenopathy and Splenomegaly

47 Anemia and Polycythemia

48 Azotemia and Urinary Abnormalities

49 Pain and Swelling of Joints

50 Back and Neck Pain

51 Headache

52 Syncope

53 Dizziness and Vertigo

54 Acute Visual Loss and Double Vision

55 Weakness and Paralysis

56 Tremor and Movement Disorders

57 Aphasia

58 Sleep Disorders

SECTION 4 Otolaryngology

59 Sore Throat, Earache, and Upper Respiratory Symptoms

SECTION 5 Dermatology

60 General Examination of the Skin

61 Common Skin Conditions

SECTION 6 Hematology and Oncology

62 Examination of Blood Smears and Bone Marrow

63 Red Blood Cell Disorders

64 Leukocytosis and Leukopenia

65 Bleeding and Thrombotic Disorders

66 Myeloid Leukemias, Myelodysplasia, and Myeloproliferative Syndromes

67 Lymphoid Malignancies

68 Skin Cancer

69 Head and Neck Cancer

70 Lung Cancer

71 Breast Cancer

72 Tumors of the Gastrointestinal Tract

73 Genitourinary Tract Cancer

74 Gynecologic Cancer

75 Tumors of the Nervous System

76 Prostate Hyperplasia and Carcinoma

77 Cancer of Unknown Primary Site

78 Paraneoplastic Endocrine Syndromes

79 Neurologic Paraneoplastic Syndromes

SECTION 7 Infectious Diseases

80 Growing Threats in Infectious Disease

81 Infections Acquired in Health Care Facilities

82 Infections in the Immunocompromised Host

83 Infective Endocarditis

84 Intraabdominal Infections

85 Infectious Diarrheas and Bacterial Food Poisoning

86 Sexually Transmitted and Reproductive Tract Infections

87 Infections of the Skin, Soft Tissues, Joints, and Bones

88 Pneumococcal Infections

89 Staphylococcal Infections

90 Streptococcal/Enterococcal Infections, Diphtheria, and Infections Caused by Other Corynebacteria and Related Species

91 Meningococcal and Listerial Infections

92 Infections Caused by Haemophilus, Bordetella, Moraxella, and HACEK Group Organisms

93 Diseases Caused by Gram-Negative Enteric Bacteria and Pseudomonads

94 Infections Caused by Miscellaneous Gram-Negative Bacilli

95 Anaerobic Infections

96 Nocardiosis, Actinomycosis, and Whipple’s Disease

97 Tuberculosis and Other Mycobacterial Infections

98 Lyme Disease and Other Nonsyphilitic Spirochetal Infections

99 Rickettsial Diseases

100 Mycoplasma pneumoniae, Legionella Species, and Chlamydia pneumoniae

101 Chlamydia trachomatis and Chlamydia psittaci

102 Infections with Herpes Simplex Virus, Varicella-Zoster Virus, Cytomegalovirus, Epstein-Barr Virus, and Human Herpesvirus Types 6, 7, and 8

103 Influenza and Other Viral Respiratory Diseases

104 Rubeola, Rubella, Mumps, and Parvovirus Infections

105 Enterovirus Infections

106 Insect- and Animal-Borne Viral Infections

107 HIV Infection and AIDS

108 Pneumocystis Pneumonia, Candidiasis, and Other Fungal Infections

109 Overview of Parasitic Infections

110 Malaria, Toxoplasmosis, Babesiosis, and Other Protozoal Infections

111 Helminthic Infections and Ectoparasite Infestations

SECTION 8 Cardiology

112 Physical Examination of the Heart

113 Electrocardiography

114 Noninvasive Examination of the Heart

115 Congenital Heart Disease in the Adult

116 Valvular Heart Disease

117 Cardiomyopathies and Myocarditis

118 Pericardial Disease

119 Hypertension

120 Metabolic Syndrome

121 ST-Segment Elevation Myocardial Infarction

122 Unstable Angina and Non-ST-Elevation Myocardial Infarction

123 Chronic Stable Angina

124 Bradyarrhythmias

125 Tachyarrhythmias

126 Heart Failure and Cor Pulmonale

127 Diseases of the Aorta

128 Peripheral Vascular Disease

129 Pulmonary Hypertension

SECTION 9 Pulmonology

130 Diagnostic Procedures in Respiratory Disease

131 Asthma

132 Environmental Lung Diseases

133 Chronic Obstructive Pulmonary Disease

134 Pneumonia, Bronchiectasis, and Lung Abscess

135 Pulmonary Thromboembolism and Deep-Vein Thrombosis

136 Interstitial Lung Disease

137 Diseases of the Pleura

138 Diseases of the Mediastinum

139 Disorders of Ventilation

140 Sleep Apnea

SECTION 10 Nephrology

141 Acute Renal Failure

142 Chronic Kidney Disease and Uremia

143 Dialysis

144 Renal Transplantation

145 Glomerular Diseases

146 Renal Tubular Disease

147 Dysuria, Urinary Tract Infections, Bladder Pain, and Interstitial Cystitis

148 Nephrolithiasis

149 Urinary Tract Obstruction

SECTION 11 Gastroenterology

150 Peptic Ulcer and Related Disorders

151 Inflammatory Bowel Diseases

152 Colonic and Anorectal Diseases

153 Cholelithiasis, Cholecystitis, and Cholangitis

154 Pancreatitis

155 Acute Hepatitis

156 Chronic Hepatitis

157 Cirrhosis and Alcoholic Liver Disease

158 Portal Hypertension

SECTION 12 Allergy, Clinical Immunology, and Rheumatology

159 Diseases of Immediate-Type Hypersensitivity

160 Primary Immune Deficiency Diseases

161 Systemic Lupus Erythematosus

162 Rheumatoid Arthritis

163 The Spondyloarthritides

164 Other Connective Tissue Diseases

165 Vasculitis

166 Osteoarthritis

167 Gout, Pseudogout, and Related Diseases

168 Other Musculoskeletal Disorders

169 Sarcoidosis

170 Amyloidosis

SECTION 13 Endocrinology and Metabolism

171 Disorders of the Anterior Pituitary and Hypothalamus

172 Diabetes Insipidus and Syndrome of Inappropriate Antidiuretic Hormone

173 Thyroid Gland Disorders

174 Adrenal Gland Disorders

175 Obesity

176 Diabetes Mellitus

177 Disorders of the Male Reproductive System

178 Disorders of the Female Reproductive System

179 Hypercalcemia and Hypocalcemia

180 Osteoporosis and Osteomalacia

181 Hypercholesterolemia and Hypertriglyceridemia

182 Hemochromatosis, Porphyrias, and Wilson’s Disease

SECTION 14 Neurology

183 The Neurologic Examination

184 Seizures and Epilepsy

185 Alzheimer’s Disease and Other Dementias

186 Parkinson’s Disease

187 Ataxic Disorders

188 ALS and Other Motor Neuron Diseases

189 Autonomic Nervous System Disorders

190 Trigeminal Neuralgia, Bell’s Palsy, and Other Cranial Nerve Disorders

191 Spinal Cord Diseases

192 Multiple Sclerosis

193 Neuromyelitis Optica

194 Acute Meningitis and Encephalitis

195 Chronic and Recurrent Meningitis

196 Peripheral Neuropathies, Including Guillain-Barré Syndrome

197 Myasthenia Gravis

198 Muscle Diseases

SECTION 15 Psychiatry and Substance Abuse

199 Psychiatric Disorders

200 Psychiatric Medications

201 Eating Disorders

202 Alcohol Use Disorder

203 Narcotic Abuse

204 Cocaine and Other Commonly Used Drugs

SECTION 16 Disease Prevention and Health Maintenance

205 Routine Disease Screening

206 Vaccines

207 Cardiovascular Disease Prevention

208 Prevention and Early Detection of Cancer

209 Smoking Cessation

210 Women’s Health

SECTION 17 Adverse Drug Reactions

211 Adverse Drug Reactions

Index

All the authority of the most trusted brand in medical content in a convenient, portable guide

The Harrison’s Manual, derived from most clinically salient content featured in Harrison's Principles of Internal Medicine, 20th Edition, delivers numerous clinical algorithms in one practical, portable resource. The Manual also includes abundant quick reference tables, plus concise text—providing rapid access to bedside information when decisions need to be made quickly. This full color summary guide covers all diseases and conditions commonly seen in inpatient general medicine, so you can be sure to find invaluable content directly to your workflow and practice.

The 20th edition has been updated to reflect the latest clinical developments in medicine.

The Manual truly makes it easy to find what you need at the point of care. The easy-to-navigate chapters cover symptoms/signs, medical emergencies, specific diseases, and care of the hospitalized patient, with a particular focus on:

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• Therapeutics
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