Goldfrank's Toxicologic Emergencies

1. Historical Principles and Perspectives
Paul M. Wax

2. Toxicologic Misfortunes and Catastrophes in History
Paul M. Wax

PART A

THE GENERAL APPROACH TO THE PATIENT

3. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman

4. Principles of Managing the Acutely Poisoned or Overdosed Patient
Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman [include eCPR, critical care dispositions]

SC1. PRINCIPLES OF ANTIDOTE STOCKING

5. Decontamination Principles: Prevention of Gastrointestinal Absorption
Lotte C. G. Hoegberg and Anne-Bolette Gude

SC2. DECONTAMINATION PRINCIPLES: PREVENTION OF DERMAL, INHALATIONAL AND OCULAR ABSORPTION

A1. ACTIVATED CHARCOAL
Silas W. Smith and Mary Ann Howland

A2. WHOLE-BOWEL IRRIGATION AND OTHER INTESTINAL EVACUANTS
Silas W. Smith and Mary Ann Howland

6. Principles and Techniques Applied to Enhance Elimination
David S. Goldfarb and Marc Ghannoum

7. Laboratory Principles
Petrie M. Rainey

8. Principles of Diagnostic Imaging
David T. Schwartz

9. Pharmacokinetic and Toxicokinetic Principles
Mary Ann Howland

PART B

THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY

SECTION I BIOCHEMICAL AND MOLECULAR CONCEPTS

10. Chemical Principles
Stephen J. Traub and Lewis S. Nelson

11. Biochemical and Metabolic Principles
Kurt C. Kleinschmidt and Kathleen A. Delaney

12. Fluid, Electrolyte, and Acid?Base Principles
Alan N. Charney and Robert S. Hoffman

13. Neurotransmitters and Neuromodulators
Steven C. Curry, Ayrn D. O'Connor, Kimberlie A. Graeme, Kirk C. Mills, and Aaron B. Skolnik

14. Withdrawal Principles
Richard J. Hamilton and [new author]

SECTION II PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS

15. Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles
Cathleen Clancy

16. Cardiologic Principles II: Hemodynamics
Robert A. Hessler

17. Dermatologic Principles
Jesse M. Lewin, Neal A. Lewin, and Lewis S. Nelson

SC3. TRANSDERMAL TOXICOLOGY
Lewis S. Nelson

18. Gastrointestinal Principles
Matthew D. Zuckerman and Richard J. Church

19. Genitourinary Principles
Jason Chu

20. Hematologic Principles
Marco L.A. Sivilotti

21. Hepatic Principles
Kathleen A. Delaney

22. Neurologic Principles
Rama B. Rao

23. Oncologic Principles
Richard Wang

24. Ophthalmic Principles
Adhi Sharma

25. Otolaryngologic Principles
William Chiang

26. Psychiatric Principles
Erin A. Zerbo and Andrea M. Kondracke

27. Renal Principles
Marc Ghannoum and David S. Goldfarb

28. Respiratory Principles
Andrew Stolbach and Robert S. Hoffman

29. Thermoregulatory Principles
Susi U. Vassallo and Kathleen A. Delaney

SECTION III SPECIAL POPULATIONS

30. Reproductive and Perinatal Principles
Jeffrey S. Fine

31. Pediatric Principles
Jeffrey S. Fine

32. Geriatric Principles
Judith C. Ahronheim and Mary Ann Howland

PART C THE CLINICAL BASIS OF MEDICAL TOXICOLOGY

SECTION I

A. ANALGESICS AND ANTIINFLAMMATORY MEDICATIONS

CASE STUDY 1

33. Acetaminophen
Robert G. Hendrickson

A3. N-ACETYLCYSTEINE
Robert G. Hendrickson and Mary Ann Howland

34. Colchicine, Podophyllin, and the Vinca Alkaloids
Joshua G. Schier

35. Nonsteroidal Antiinflammatory Drugs
William J. Holubek

36. Opioids
Lewis S. Nelson and Dean Olsen

A4. OPIOID ANTAGONISTS
Lewis S. Nelson and Mary Ann Howland

SC4. INTERNAL CONCEALMENT OF XENOBIOTICS
Jane M. Prosser

SC5. HARM REDUCTION FOR OPIOID OVERDOSE
Josh Lee

37. Salicylates
Daniel M. Lugassy

A5. SODIUM BICARBONATE
Paul M. Wax

B. FOOD, DIET, AND NUTRITION

CASE STUDY 2

38. Botulism
Howard L. Geyer

A6. BOTULINUM ANTITOXIN
Silas W. Smith and Howard L. Geyer

39. Food Poisoning
Michael Tunik

40. Dieting Xenobiotics and Regimens
Jeanna M. Marraffa

41. Athletic Performance Enhancers
Susi U. Vassallo

42. Essential Oils
Lauren Kornreich Shawn

43. Herbal Preparations
Oliver Hung

44. Vitamins
Beth Y. Ginsburg

45. Iron
Jeanmarie Perrone

A7. DEFEROXAMINE
Mary Ann Howland

C. PHARMACEUTICALS

CASE STUDY 3

46. Pharmaceutical Additives
Sean P. Nordt and Lisa E. Vivero

47. Antidiabetics and Hypoglycemics/Antiglycemics
George M. Bosse

A8. DEXTROSE (d-Glucose)
Larissa Velez

A9. OCTREOTIDE
Mary Ann Howland and Silas W. Smith

48. Antiepileptics
Suzanne Doyon

A10. L-carnitine
Mary Ann Howland

49. Antihistamines and Decongestants
Sophie Gosselin

A11. PHYSOSTIGMINE SALICYLATE

 

For decades, one name has been synonymous with the most respected, rigorous perspective on medical toxicology and treatment of poisoned and overdosed patient: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank's delivers essential, patient-centered coverage of every aspect of poison management. The editors and author are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to evidence-based treatment strategies.

Fully referenced and featuring a consistent organization, Goldfrank's begins with an in-depth examination of general principles of medical toxicology. It then progresses to the biochemical principles of the molecular basis of toxicology, and provides detailed insight into how xenobiotics affect vital organs, and systems throughout the body, Next, a wide spectrum of clinically important exposures " including drugs, plants, metals, household products, occupational and environmental xenobiotics and covered within logical categories for easy access of information. Finally, the book concludes with sections on principles of practicing clinical toxicology in today's challenging healthcare environment. All chapters have been thoroughly rewritten and updated with new content on medical, clinical, and chemical toxicology