Liver Transplantation. Clinical Assessment and Management

PART 1 When to Refer a Patient for Liver Transplantation

1 Overview on organ donation and liver transplantation

Michael Ronan Lucey

2 Predicting Outcomes and Use and Abuse of Prognostic Models

Moira B. Hilscher  and Patrick S. Kamath

PART 2 Selection, Assessment and Management on the List

3 Assessment of the potential transplant recipient

Michael Volk

4 Frailty and pre-habilitation

Armstrong MJ, Lai JC

5 Alcohol use (excluding alcohol related liver disease), Tobacco, Marijuana and Illicit Drugs

John P. Rice

6 The Role of the Psychiatric Consultant in the Selection, Assessment and Management of Liver Transplant Patients

RM Weinrieb

7 When Liver Transplant Patients do not Adhere to Therapeutic Plans

Kerry Webb and Rowena Jones

8 Liver transplant assessment for young people : addressing the needs of young people with liver disease

M Samyn, J Day

9 Assessment and Management of the patient with Hepatitis C

Emma L. Hathorn and David J. Mutimer

10 MANAGEMENT OF HBV INFECTION PRE-TRANSPLANTATION

Bruno ROCHE, Didier SAMUEL

11 Transplantation For The Management Of Malignancy

Adiba I. Azad, Julie K. Heimbach and Gregory J. Gores

12 Assessment and management of the liver transplant candidate with acute-on-chronic liver failure

Giovanni Perricone and Rajiv Jalan

13 Assessment and Management of the transplant candidate with alcohol-associated liver disease

Stéphanie Faure, Magda Meszaros, Lucy Meunier, Hélène Donnadieu-Rigole, Georges-Philippe Pageaux

14 NAFLD as an indication for liver transplantation

P. Horn, P.N. Newsome

15 Consent

Christopher J.E. Watso

16 Prehabilitation and General Management

Matt Armstrong  and F. Williams

17 Removal of Patients from the Liver Transplant Waiting List

John O’Grady

18 Palliative Care and Liver Transplantation

Mina Rakoski  and Puneeta Tandon

PART 3 Transplantation for Acute Liver Failure

19 Assessment of the Patient with Acute Liver Failure

Ashley Barnabas and John O’Grady

20 Management of the Patient with Fulminant Hepatic Failure Awaiting Liver Transplantation

Robert J. Fontana

PART 4 Donation and Allocation

21 Ethical and Legal Aspects of Organ Donation    

Jessica Mellinger

22 Liver allocation, including Principles of organ allocation

Parita Patel and Michael Charlton

23 Living Donor Liver Transplant (LDLT) in Children

Adebowale A. Adeyemi, Elizabeth B. Rand, Kim M Olthoff

24 Living liver donation in adults

Mohamed Rela and Ashwin Rammohan

25 Deceased Liver Donors: Standard and Expanded Criteria

Shareef Syed and Sandy Feng

26 Donor Transmitted Disease

James Neuberger

27 LIVER DONATION AND PRESERVATION

Navneet Tiwari, Hynek Mergental

28 Liver Retrieval and Preservation

Carlo DL Ceresa, Brian R Davidson, Peter J Friend and Rutger J Ploeg

29 Alternatives to Whole Graft Liver Transplantation

Paolo Muiesan, Alessandro Parente, Hector Vilca-Melendez

30 Surgical aspects of deceased donor transplantation

Amit Nair, K.V Narayanan Menon, Cristiano Quintini and Charles Miller

PART 5 Care of the Liver Transplant Recipient

31 Outcomes after liver transplantation

James Neuberger

32 Out-patient follow-up of liver transplant recipients

Amardeep Khanna &  James Ferguson

33 Medication adherence

Maureen Whitsett, Josh Levitsky

34 Transitional Care

Fiona Thompson

35 Managing the liver transplant recipient with abnormal liver blood tests

Joanna A Leithead

36 The Immune System in Liver Transplantation: Rejection vs. Tolerance

Palak J. Trivedi and Nick D. Jones

37 Immunosuppressive Medications – Liver Transplantation

 Mitchell T, MacQuillan G

38 Immunosuppression in Liver Transplantation

Nicholas Lim and John R. Lake

39 : Patterns of Liver Allograft Rejection

G. W. McCaughan, K. Liu, A. Majumdar, P. Bertolino, D.G. Bowen, S. I. Strasser

40 De novo autoimmune hepatitis

James Neuberger

41 Managing rejection

Neil Halliday & Douglas Thorburn

42 Withdrawal of Immunosuppression after liver transplantation

Luca Toti, Tommaso Maria Manzia, Francesca Blasi, Giuseppe Tisone.

43 Liver Transplant Pathology

Owen L Cain and Stefan G Hübscher

44 Care of the Liver Transplant Recipient: Management of Renal Function

Andres F. Carrion, Paul Martin

45 Managing Cardiovascular Risk in the Liver Transplant Recipient

Manhal Izzy and Kymberly D. Watt

46 Bone Disease in Liver Transplantation

John Ayuk

47 Diagnosis and Management of Recurrent Autoimmune Liver Disease

Fernanda Q Onofrio, Nazia Selzner, Gideon M Hirschfield

48 NAFLD and NASH in the patient after liver transplantation

P. Horn, P.N. Newsome

49 Recurrent Metabolic Diseases

James Neuberge

50 Treatment of Hepatitis C in the Transplant Setting

Jeffrey Kahn and Norah A. Terrault

51 MANAGEMENT OF HBV INFECTION POST-TRANSPLANTATION

Bruno ROCHE, Didier SAMUEL

52 Antimicrobial prophylaxis following liver transplantation

Michael J Williams, Peter C Hayes

53 Cytomegalovirus and the liver transplant recipient

James Ferguson

54 Post-liver transplant infections

Miruna David, Ahmed El-Sharkawi

55 De novo malignancies after liver transplantation

Simone I Strasser, Ken Liu, Avik Majumdar, Geoffrey W McCaughan

56 Post-transplant lymphoproliferative disorders (PTLD).

Jose I. Herrero

57 Quality of life and Employment after liver transplantation

Santiago Tome, Esteban Otero, and Michael Lucey

58 Sexual function, fertility and pregnancy in liver disease and after liver transplantation

Patrizia Burra, Salvatore Stefano Sciarrone, Patrizio Bo

59 Common Drug Interactions

Amanda Smith

60 Immunization and Liver Transplantation

Erin Spengler

Postscript

Index  

"Welcome to the second edition of Liver Transplantation. Since the first edition, there have been many changes in the management of patients with liver disease, both before and after transplantation and this new edition reflects this. As with the first edition, the aim of the volume is to provide a concise, practical and authoritative guide for junior medical staff and other health professionals working in liver transplant units, for health care professionals looking after those patients with liver disease who are or may become liver transplant candidates and those following liver transplantation. We have expanded both the number and reach of authors, with consequent increase in chapters. We have sought to represent the breadth of liver transplant medicine across Europe and North America, while recognizing also the role of liver transplantation in the rest of the world. We appreciate that this means some duplication and occasional divergence of views. We have intentionally retained these so that each chapter is entire of itself and the reader understands where there is uncertainty. We are very grateful to the authors who have written and revised their contributions during the height of the Covid pandemic. We are grateful to those at Wiley Blackwell, especially Jennifer Seward and Pri Gibbons, for the help and patience and, most importantly to our partners and children who have been patient with us during the preparation of this second edition"--