Nutraceuticals and Natural Product Derivatives. Disease Prevention and Drug Discovery

1 Natural Food Sources for the Control of Glycemia and the Prevention of Diabetic Complications 1
Carlo Pesce, Carla Iacobini, and Stefano Menini

2 Anti‐Aging Effects of Sulfur‐Containing Amino Acids and Nutraceuticals 25
Geetika Garg, Abhishek Kumar Singh, Sandeep Singh, and Syed Ibrahim Rizvi

3 Garcinia Fruits: Their Potential to Combat Metabolic Syndrome 39
Oliver John, Lindsay Brown, and Sunil K. Panchal

4 Pro‐Angiogenic and Anti‐Angiogenic Effects of Small Molecules from Natural Products 81
Jingyi Ma and Xuelin Zhou

5 Nutraceuticals and Natural Product Derivatives in the Premises of Disease Prevention 111
Mohammad Fahad Ullah, Showket Hussain Bhat, and Faisel M. Abu‐Duhier

6 Honey‑ and Propolis‐Mediated Regulation of Protein Networks in Cancer Cells 137
Ammad Ahmad Farooqi, Mirna Azalea Romero, Aliye Aras,Muhammad Zahid Qureshi, and Lara Hanna Wakim

7 Antiproliferative Effects and Mechanism of Action of Phytosterols Derived from Bioactive Plant Extracts 145
Gabriel Lopez‐Garcia, Amparo Alegria, Reyes Barbera, and Antonio Cilla

8 Yerba Mate (Ilex paraguariensis A. St. Hil.): A Promising Adjuvant in the Treatment of Diabetes, Obesity, and Metabolic Syndrome 167
Vanesa Gesser Correa, Rubia Carvalho Gomes Correa, Tatiane Francielli Vieira, Adelar Bracht, Rosane Marina Peralta, and Eloa Angelica Koehnlein

9 Role of Natural Antioxidants from Selected Plants Belonging to the Scrophulariaceae and Buddlejaceae Families in the Prevention and Treatment of Neurodegenerative Diseases 183
Cigdem Kahraman, Zeliha S. Akdemir, and I. Irem Tatli

10 Recent Trends in Drug Discovery against Alzheimer’s Disease: Use of Natural Products and Nutraceuticals from Botanicals 237
Sudatta Maity, Samapika Nandy, and Abhijit Dey

11 Therapeutic Potential of Metalloherbal Nanoceuticals: Current Status and Future Perspectives 279
Shazia Usmani, Muhammad Arif, and Syed Misbah Hasan

12 Green Tea Polyphenols: A Putative Mechanism for Cytotoxic Action against Cancer Cells 305
Mohd Farhan, Uzma Shamim, and S.M. Hadi

13 Nature’s Armamentarium against Malaria: Antimalarials and Their Semisynthetic Derivatives 333
Fyaz M.D. Ismail

14 Nutraceutical‐Based Pharmacological Intervention in the Management of Liver Diseases 375
Aaliya Shah and Syed Mudassar

References 
Index

Introduces readers to the growing applications of nutraceuticals and other natural product derivatives.

This comprehensive book presents a prophylactic and therapeutic approach to chronic disease prevention strategy by highlighting the translational potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies. It also shares the experiences of highly reputed experts working in the area of phytomedicine and nutraceutical agents in chemoprevention, to promote the significance of natural products and dietary factors as an elite priority for containing chronic diseases in the human population.

Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery starts by examining natural food sources for the control of glycemia and the prevention of diabetic complications. It then looks at the anti-aging effects of sulfur-containing amino acids and nutraceuticals, and the potential of garcinia fruits to combat metabolic syndrome. Other topics covered include honey- and propolis-mediated regulation of protein networks in cancer cells; recent trends in drug discovery against Alzheimer’s disease; the therapeutic potential of metalloherbal nanoceuticals; and much more.

• Offers an alternative, natural approach to the prevention of chronic diseases
• Emphasizes the potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies
• Features contributions from world-renowned experts in the field of phytomedicine and nutraceutical agents in chemoprevention
• Includes prevention strategies in normal/risk populations through routine inclusion of specific dietary regimens and as therapeutic strategy for better management through adjuvant interventions with conventional treatment protocols

Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery will appeal to graduate students and professionals in cell and molecular biology, translational research, pharmacology/drug discovery, medicinal chemistry, and clinical nutrition.