Sherlock's Diseases of the Liver and Biliary System

Contributors
Preface to the Thirteenth Edition
Preface to the First Edition
About the Companion Website

1 Anatomy and Function
Jay H. Lefkowitch

2 Liver Function in Health and Disease: Clinical Application of Liver Tests
George Mells & Graeme Alexander

3 Biopsy of the Liver
David Patch & Tu Vinh Luong

4 Coagulation in Cirrhosis
Nicolas M. Intagliata & Stephen H. Caldwell

5 Acute Liver Failure
Shannan R. Tujios & William M. Lee

6 Hepatic Fibrogenesis
Meena B. Bansal & Scott L. Friedman

7 Non-Invasive Assessment of Fibrosis and Cirrhosis
Avik Mujamdar & Massimo Pinzani

8 Hepatic Cirrhosis
P. Aiden McCormick & Rajiv Jalan

9 Ascites
Guadalupe Garcia-Tsao

10 Hepatic Encephalopathy in Patients with Cirrhosis
Marsha Y. Morgan

11 Portal Hypertension in Cirrhosis
Jaime Bosch & Annalisa Berzigotti

12 Vascular Disorders of the Liver and Extrahepatic Portal Hypertension
Dominique-Charles Valla

13  Jaundice and Cholestasis
Peter L. M. Jansen

14 Gallstones and Benign Biliary Disease
James S. Dooley, Kurinchi S. Gurusamy & Brian R. Davidson

15 Malignant Biliary Diseases
Rahul S. Koti & John Bridgewater

16 Fibropolycystic Liver Diseases and Congenital Biliary Abnormalities
Nedim Hadžiæ & Mario Strazzabosco

17 Primary Biliary Cholangitis
David E. J. Jones

18 Sclerosing Cholangitis
Tom Hemming Karlsen & Kirsten Muri Boberg

19 Autoimmune Hepatitis and Overlap Syndromes
Ashnila Janmohamed & Gideon M. Hirschfield

20 Enterically Transmitted Viral Hepatitis: Hepatitis A and Hepatitis E
Rinjal D. Brahmbhatt & Anna S. F. Lok

21 Hepatitis B
Anna S. F. Lok

22 Hepatitis D
Patrizia Farci & Grazia Anna Niro

23 Hepatitis C
Geoffrey Dusheiko

24 Drug-Induced Liver Injury
Frank W. DiPaola & Robert J. Fontana

25 Alcohol and the Liver
Stephen Stewart & Ewan Forrest

26 Iron Overload States
Paul Adams & Heinz Zoller

27 Wilson Disease
Eve A. Roberts & Karl Heinz Weiss

28 Non-Alcoholic Fatty Liver Disease
Timothy Hardy & Christopher P. Day

29 Nutrition and Chronic Liver Disease
Manuela Merli

30 Pregnancy and the Liver
Rachel H. Westbrook & Catherine Williamson

31 The Liver in the Neonate, in Infancy and Childhood
Deirdre A. Kelly & Susan M. Siew

32 The Liver in Systemic Diseases
James S. Dooley & Christopher McNamara

33 The Liver in Infections
Sanjay Bhagani & Ian Cropley

34 Imaging of the Liver and Diagnostic Approach of Space-Occupying Lesions
Neil H. Davies & Dominic Yu

35 Benign Liver Tumours
Ian R. Wanless

36 Primary Malignant Neoplasms of the Liver
Adam Doyle & Morris Sherman

37 Hepatic Transplantation
Lindsay Y. King & Carl L. Berg

38 Hepatic Transplantation and HBV, HCV and HIV Infections
Norah A. Terrault

Index

A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists

This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category.

Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website.

• Internationally recognized and loved, world-renowned hepatology book, first published in 1955
• Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation
• Full colour throughout with 700 illustrative figures
• Wide faculty of international contributors

Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.

About the Author

James S. Dooley. The Royal Free Hospital, London, UK.
Anna S. Lok. Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Guadalupe Garcia-Tsao. Yale University School of Medicine, VA-CT Healthcare System, CT, USA.
Massimo Pinzani. UCL Institute for Liver and Digestive Health. London, UK.