Medication-Resistant Epilepsy. Diagnosis and Treatment

Fifty million people worldwide have epilepsy and yet up to 35% of patients experience seizures that are resistant to anti-epileptic drugs. Patients with medication-resistant epilepsy have increased risks of premature death, psychosocial dysfunction and a reduced quality of life. This key resource delivers guidance for all clinicians involved in caring for patients with medication-resistant epilepsy in order to reduce these risks. Covering the epidemiology, biology, causes and potential treatments for medication-resistant epilepsy, this definitive and focused text reviews the clinical care needs of patients. Guidance is practical and includes treatment for specialized groups including pediatric patients and those with psychiatric comorbidities. Several promising non-pharmacologic interventions available for patients, such as surgery, neuromodulation diet therapy and botanical treatment are explored in detail. Leading international figures from a range of disciplines bring their expertise together holistically in this essential manual.

• Focuses on the clinical care needs of patients, making it an essential guide for practicing clinicians
• A broad yet detailed scope allows for the entire text to be read, bringing together topics holistically in an accessible handbook format
• Treatments covered are cutting-edge, with the latest research and evidence discussed in detail meaning clinicians will be able to make fully informed decisions for their patients' care

John M. Stern, Geffen School of Medicine at UCLA, Los Angeles, CA
John Stern is a Professor and Director of the Epilepsy Clinical Program in the Department of Neurology at the Geffen School of Medicine, University of California, Los Angeles.

Raman Sankar, Geffen School of Medicine at UCLA, Los Angeles, CA
Raman Sankar is Chief of Pediatric Neurology and Distinguished Professor in the Departments of Neurology and Paediatrics at the Geffen School of Medicine, University of California, Los Angeles.

Michael Sperling, Jefferson Hospital for Neurosciences, Philadelphia, PA
Michael Sperling is the Director of Jefferson Comprehensive Epilepsy Center, Philadelphia, and Professor of Neurology at Thomas Jefferson University, Philadelphia.