Medication-Induced Movement Disorders

Description

Medications that may produce movement disorders are widely used. The resulting disorders are often highly disconcerting for the patient and their relatives, especially when the connection between medication and disorder is not recognized. However, ascribing an adverse drug effect to medication exposure is often difficult, especially when the side effect is rare. Covering various drugs - including the major classes of medications working primarily on the brain, specifically antipsychotics and antidepressants – this all-encompassing review of medication-induced movement disorders aids early recognition and improved treatment. The problem of what to do when the offending medication cannot be reduced is also reviewed. It discusses the best options for evaluation and treatment, including medical imaging and deep brain stimulation, and guides the clinician in managing the disorder, making this a vital reference for medical specialists and consultants in neurology and neuropharmacology and any clinician seeing patients on medications crossing the blood-brain barrier.

• Discusses current treatment strategies for medication-induced movement disorders, providing the reader with up-to-date knowledge of medications which can cause movement disorders and specific symptoms and how to approach them
• Written in an accessible style by internationally renowned experts in each of the disorders discussed
• Covers disorders and syndromes with potential medical-legal implications

Contents

List of contributors
Dedication
Introduction
1. Acute akathisia Drew S. Kern and Anthony E. Lang
2. Acute dystonia Anne Marthe Meppelink and Mark J. Edwards
3. Neuroleptic malignant syndrome Atbin Djamashidian and Sean S. O'Sullivan
4. Serotonin syndrome Dimitrios A. Nacopoulos and Hubert H. Fernandez
5. Neuroleptic Parkinsonism Joseph H. Friedman
6. Tardive syndromes Daniel Tarsy and Raminder Parihar
7. Tardive dyskinesia treatment Tracy M. Jones, Israt Jahan and Theresa A. Zesiewicz
8. Atypical antipsychotics and movement disorders Rob M. A. de Bie
9. Restless legs syndrome Roongroj Bhidayasiri and Pattamon Panyakaew
10. Medication-induced tremors Peter A. Lewitt
11. L-Dopa dyskinesias Juan Ramirez-Castaneda and Joseph Jankovic
12. VPA, lithium, amiodarone and other non-DA Michael Silver and Stewart A. Factor
13. Anti-depressants and movement disorders Gilles Fénelon
14. Ataxia Marina Sanchez Abraham and Oscar S. Gershanik
15. Myoclonus and asterixis P. D. Thompson, T. J. Kleinig and T. E. Kimber
16. Imaging in medication-induced Parkinsonism Danna Jennings
17. Deep brain stimulation for Tardive disorders Bernardo Rodrigues and Kelvin L. Chou
Index.

Author

Joseph H. Friedman, Department of Neurology, Brown University
Joseph H. Friedman is the Stanley Aronson Chair in Neurodegenerative Disorders at Butler Hospital, Professor of Neurology and Chief of the Division of Movement Disorders in the Department of Neurology at the Alpert Medical School of Brown University, Providence, RI, and Adjunct Professor in the School of Pharmacy at the University of Rhode Island, Kingston, RI, USA.