No hay productos en el carrito



Cerebral Small Vessel Disease
Pantoni, L. — Gorelick, P.
1ª Edición Mayo 2014
Inglés
Tapa dura
371 pags
990 gr
20 x 26 x 3 cm
ISBN 9781107031661
Editorial CAMBRIDGE
LIBRO IMPRESO
-5%
173,32 €164,65 €IVA incluido
166,65 €158,32 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
Description
Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about its causes, diagnosis, prevention and treatment. This volume brings together contributions from leading international experts in the field and discusses pathogenesis, pathophysiology, clinical and radiologic manifestations, prevention and treatment modalities, and future directions for research and practice. Genetic forms of SVD are discussed, as well as the rapid development of neuroimaging techniques as tools for screening and treatment. This authoritative book is essential reading for neurologists, stroke physicians, geriatricians, and interventional neuroradiologists, as well as researchers in the fields of aging and dementia.
- Gives readers an understanding of every aspect of the disease, including the underlying genetic mechanisms and other predisposing factors
- Chapters are written by leading international authorities and draw on personal experience of diagnosis and management
- New developments are presented to give readers the most up-to-date information available
Contents
Preface
Part I. Classification, Pathology and Basic Aspects:
1. Definition and classification of small vessel diseases Leonardo Pantoni
2. Pathology of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi
and Hatsue Ishibashi-Ueda
3. Pathological aspects of the ischemic consequences of small vessel disease
on brain parenchyma Margaret Esiri and Elisabet Englund
4. Pathological aspects of the hemorrhagic consequences of small vessel diseases
on the brain Johannes Attems and Kurt A. Jellinger
5. Experimental animal models of cerebral small vessel disease Atticus H. Hainsworth
and Hugh S. Markus
6. Sporadic small vessels disease: pathogenic aspects Joanna M. Wardlaw and
Leonardo Pantoni
7. Pathogenic aspects of hereditary small vessel disease of the brain Anne Joutel
8. Hereditary cerebral small vessel disease and role of genetic factors Christian
Opherk and Martin Dichgans
9. The link between large artery aging and cerebral small vessel disease Angelo
Scuteri and Edward G. Lakatta
10. The neurovascular unit and possible influences on cerebral small vessel
disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T. Hawkins
Part II. Neuroimaging and Laboratory Aspects:
11. Conventional brain imaging of white matter lesions Franz Fazekas, Christian
Enzinger, Stefan Ropele and Reinhold Schmidt
12. Conventional imaging of lacunar infarcts Eric Jouvent and Hugues Chabriat
13. Imaging of hemorrhagic cerebral small vessel disease Jennifer Linn, Steven
Greenberg and Anand Viswanathan
14. Nonconventional MR techniques for imaging cerebral small vessel disease
David Nyenhuis and Glenn T. Stebbins
15. Cerebral hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte
L. Allan and Klaus P. Ebmeier
16. Markers of endothelial dysfunction, oxidative stress and inflammation in
cerebral small vessels disease Francesca Pescini and Rosanna Abbate
17. Cerebral small vessel disease: cerebrospinal fluid aspects Anders Wallin
and Maria Bjerke
Part III. Clinical Aspects of Cerebral Small Vessel Disease:
18. Acute stroke syndromes caused by small vessel disease Mark I. Boulos, Ranjith
K. Menon, Richard I. Aviv, Sandra E. Black and Richard H. Swartz
19. Cognitive consequences of cerebral small vessel disease José M. Ferro,
Ana Verdelho and Sofia Madureira
20. Motor, stance and balance consequences of cerebral small vessel diseases
H. Baezner, Christian Blahak and Michael G. Hennerici
21. Psychiatric consequences of small vessel disease Perminder S. Sachdev and
Sharon Reutens
22. Consequences of cerebral small vessel disease: disability, mortality and
prognosis Anna Poggesi, Leonardo Pantoni and Domenico Inzitari
23. Clinical aspects of genetic forms of small vessel disease Maria Teresa Dotti
and Antonio Federico
24. Interaction between cerebral small vessel disease and neurodegenerative
changes Wiesje M. van der Flier and Raj Kalaria
Part IV. Therapeutic Aspects: Prevention, Future Directions, and Possibilities:
25. Risk factors as possible targets for prevention of small vessel disease
Vincent Mok, Philip B. Gorelick and Christopher Chen
26. Treatment approaches for lacunar strokes Makoto Nakajima, Thalia Field and
Oscar R. Benavente
27. Cerebral small vessels disease imaging as a surrogate marker for clinical
trials Reinhold Schmidt, Margherita Cavalieri and Marisa Loitfelder
28. Cerebral small vessel disease: a look to the future Philip B. Gorelick and
Leonardo Pantoni
Index.
About the Authors
Leonardo Pantoni, Azienda Ospedaliero Universitaria Careggi
Leonardo Pantoni, MD, PhD is Staff Neurologist, Azienda Ospedaliero Universitaria
Careggi, Florence, Italy.
Philip B. Gorelick, College of Human Medicine, Michigan State
University
Philip B. Gorelick, MD, MPH is Professor of Translational Science and Molecular
Medicine, Michigan State University College of Human Medicine, and Medical Director,
Hauenstein Neuroscience Center, Mercy Health at Saint Mary's, Grand Rapids,
Michigan, USA.
© 2025 Axón Librería S.L.
2.149.0