Neuroimaging of Sleep and Sleep Disorders

Description

This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with sleep disorders. There are detailed reviews of new neuroimaging techniques – including CT, MRI, advanced MR techniques, SPECT and PET – as well as image analysis methods, their roles and pitfalls. Neuroimaging of normal sleep and wake states is covered plus the role of neuroimaging in conjunction with tests of memory and how sleep influences memory consolidation. Each chapter carefully presents and analyzes the key findings in patients with sleep disorders indicating the clinical and imaging features of the various sleep disorders from clinical presentation to neuroimaging, aiding in establishing an accurate diagnosis. Written by neuroimaging experts from around the world, Neuroimaging of Sleep and Sleep Disorders is an invaluable resource for both researchers and clinicians including sleep specialists, neurologists, radiologists, psychiatrists, psychologists.

Features

• Most comprehensive collection of information regarding the neuroimaging of sleep and sleep disorders
• Contains new information on the role of neuroimaging in sleep medicine
• Includes real-life case studies

Table of Contents

Preface

Part I. Introduction:
1. The role of neuroimageing in sleep and sleep disorders
2. Neuroanatomy and physiology of sleep and wakefulness
3. Fundamentals of structural MR imaging
4. Fundamentals of MRI for assessing brain function and metabolism
5. Fundamentals of PET scanning
6. Fundamentals of single-photon emission computed tomography (SPECT) and SPECT/CT imaging
7. Fundamentals of transcranial B-mode sonography
8. Fundamentals of magnetoencephalography
9. Fundamentals of low-resolution brain electromagnetic tomography
10. Methodology of combined EEG and fMRI

Part II. Neuroimaging of Wakefulness and Sleep:
11. Neuroimaging of wakefulness
12. Neuroimaging of phasic and non-phasic NREM activities
13. Functional connectivity in wakefulness and sleep
14. Functional neuroimaging of human REM sleep
15. Complementarity of dream research and neuroimaging of sleep

Part III. Neuroimaging, Sleep Loss and Circadian Misalignment:
16. Functional neuroimaging of sleep deprivation
17. Neuroimaging of attention and alteration of processing capacity in sleep-deprived persons
18. Economic decision-making and the sleep-deprived brain
19. Functional imaging of inter-individual differences in response to sleep deprivation
20. Neuroimaging the interaction between circadian and homeostatic processes
21. Neuroimaging the effects of light on non-visual brain functions

Part IV. Sleep and Memory:
22. Memory systems, sleep and neuroimaging

Part V. Neuroimaging of Sleep Disorders:
(a) Insomnias and Circadian Rhythm Disorders:
23. Imaging causes and consequences of insomnia and sleep complaints
24. Functional neuroimaging of primary insomnia
25. Sleep neuroimaging in depression and schizophrenia
(b) CNS Hypersomnias:
26. Structural neuroimaging of narcolepsy
27. Functional neuroimaging of narcolepsy
28. Neuroimaging of treatment response in narcolepsy
29. Modafinil effects in narcolepsy
30. Neuroimaging of Kleine–Levin syndrome
Cases: Hypersomnia:
31. Neuroimaging of cataplexy
(c) Sleep-related Breathing Disorders:
32. Structural brain neuroimaging changes in obstructive sleep apnea
33. Imaging the airway in obstructive sleep apnea
34. Neuroimaging cognitive effects in obstructive sleep apnea
35. Neuroimaging of autonomic dysfunction and ventilatory control in obstructive sleep apnea
36. Neuroimaging of treatment effects in obstructive sleep apnea
37. Structural and functional neuroimaging of congenital central hypoventilation syndrome
(d) Parasomnias:
38. Neuroimaging of disorders of arousal and other parasomnias
39. Neuroimaging of Parkinson's disease and multiple system atrophy in patients with sleep disturbance
40. Neuroimaging of idiopathic REM sleep behaviour disorder
41. Cardiac (123)I-MIBG scintigraphic findings and REM sleep behaviour disorder
42. Neuroimaging and post-traumatic stress disorder
Cases: Parasomnias:
43. Neuroimaging of sleepwalking
44. Neuroimaging of the brainstem in parasomnia overlap disorder
45. Nocturnal wanderings and arachnoid cyst
(e) Other Sleep-related Neurological Disorders:
46. Structural and functional neuroimaging of restless legs syndrome and periodic limb movements in sleep
47. Functional neuroimaging of dopamine, iron and opiates in restless legs syndrome
48. Neuroimaging and fatal familial insomnia
49. Neuroimaging of sleep-related epilepsies
50. Sleep, neuroimaging and polysomnography of Wilson's disease
(f) Medication Effects:
51. Functional neuroimaging: sedating medication effects
52. Functional neuroimaging of alerting medication effects
Cases: Medication Effects:
53. Zolpidem-induced parasomnias
Index.