Asphyxia in Neonates

Preface

 

Chapter 1

Perinatal asphyxia, hypoxia, ischemia and newborn by Miljana Z Jovandaric

 

Chapter 2

Pathophysiology of asphyxia in pregnancy by Stefan Dugalic

 

Chapter 3

Causes of perinatal asphyxia by Sandra Babic

 

Chapter 4

Multiorgan postasphyctic damage by Miljana Z Jovandaric

 

Chapter 5

Pathogenesis of ischemia-reperfusion brain damage by Miljana Z Jovandaric

  

Chapter 6

Lipid peroxidation during asphyxia by Miljana Z Jovandaric

 

Chapter 7

Lipids - a predictive parameter of therapeutic hypothermia (cooling therapy) in asphyxiated newborns by Miljana Z Jovandaric

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In severe asphyxia, lipid peroxidation occurs. Neonatal lipid concentration may indicate the severity of asphyxia and be a reason for needing cooling therapy. Asphyxia in Neonates describes the results of research into the impact oxygen deficits in neonates. The physiological consequences of asphyxiated newborn infants include changes in the pH of plasma and changes in lipid concentrations. These changes can result in apoptosis, loss of cell membrane integrity, and damage to the brain.

• Reviews pathophysiology of asphyxia
• Describes the influence of asphyxia on lipids concentrations
• Summarizes the weight distribution of neonates with asphyxia based on lipid concentration
• Illustrates the use of lipids as an indicator of prognosis following asphyxia
• Provides guidance for lipids parameters in cooling therapy

Miljana Z. Jovandaric, MD, PhD, was born in Serbia. She graduated at the Faculty of Medicine, University of Belgrade, and completed her pediatric specialization in 1999 at the University Children's Hospital, Belgrade. Dr. Jovandaric completed her specialization in neonatology in 2003. She defended her master's thesis, "Analysis of lipid infants in women suffering from gestational diabetes mellitus (GDM)," in 2006 and doctoral dissertation, "Effect of hypoxia on electrolyte and lipid levels in term newborns," in 2018 as part of the medical faculty at University of Belgrade, Serbia. Dr. Jovandaric has been a research associate since 2020 as part of the medical faculty of University of Belgrade, Serbia. Author and co-author of 106 scientific papers presented at national and international conferences and journals, she's head of the Department of Sick Newborns at the Clinic for Gynecology and Obstetrics, Department of Neonatology, University Clinical Center of Serbia, Belgrade. Dr. Jovandaric has edited and/or contributed to the following books: Childbirth: Placenta Abruption and Delivery Method; Selected Topics in Myasthenia Gravis: Maternal and Neonatal Outcome of Pregnancies with Autoimmune Myasthenia Gravis; Apoliproteins, Triglicerides and Cholesterol: Signicance of Lipid and Lipoprotein in Organism; and Veganism: A Fashion Trend or Food as a Medicine – Veganism: A New Approach to Health.

Stefan Dugalic, Ass, MD PhD, is a gynecology and obstetrics specialist, and master manager in the medical/health care system. In 2017, he joined the Clinic for Gynecology and Obstetrics, University Clinical Centre of Serbia , as a doctor of medicine, and later as a gynecolory and obstetrics specialist in 2021. In 2019, he participated in the project of the Ministry of Education, Science and Technology developing clinical epidemiological research of health disorders of public health significance for the population of Serbia (project No. 175025). Dr. Dugalic received his MD from the School of Medicine at the University of Belgrade in 2016, where he also completed his education as a specialist in the field of human reproduction in 2017 and in the field of gynecology and obstetrics in 2021.

Sandra Babic, MD, was born in Belgrade, Serbia, and graduated from the Medical Faculty of the University of Belgrade. At the same faculty in 2015/2016, she enrolled and completed the Specialist Academic Studies (SAS) program in the field of human reproduction. She completed her studies as a specialist in gynecology and obstetrics in 2020. She has been with the Clinic for Gynecology and Obstetrics UKCS since 2013, first as a volunteer and now as a clinical doctor. Dr. Babic has published several works in foreign and domestic professional journals.