Textbook of Human Reproductive Genetics

1. Basic genetics and cytogenetics: a brief reminder Karen Sermon
2. Application of whole-genome technologies to ART Elia Fernandez Gallardo, Thomas Lefevre, Koen Theunis, and Thierry Voet
3. Meiosis: how to get a good start in life Ursula Eichenlaub-Ritter
4. Chromosomes in early human embryo development: incidence of chromosomal abnormalities, underlying mechanisms, and consequences for development Esther B. Baart, Effrosyni Chavli, and Diane Van Opstal
5. DNA is not the whole story: transgenerational epigenesis and imprinting Ashwini Balakrishnan and J. Richard Challiet
6. Genes are not the whole story: retrotransposons as new determinants of male fertility Patricia Fauque and Deborah Bourc'his
7. Chromosomal causes of infertility: the story continues Svetlana A. Yatsenko and Aleksandar Rajkovic
8. Genetics of human male infertility Stephane Viville and Ozlem Okutman
9. Genetics of human female infertility Svetlana A. Yatsenko and Aleksandar Rajkovic
10. Preconception genetics analysis and screening in IVF Juan Jose Guillen and Rita Vassena
11. Genetic counseling in ART Christine De Die-Smulders and Ron van Golde
12. Mitochondrial genetics in reproductive medicine Claudia Spits and Filippo Zambelli
13. Preimplantation genetic diagnosis Jan Traeger-Synodinos and Carmen Rubio Lluesa
14. Epigenetics and ART Aafke P. A. van Montfoort
15. Ethical considerations in human reproductive genetics Guido de Vert and Wybo Dondorp.

A basic understanding of human genetics is vital for all those working in the field of assisted human reproduction. Genetic makeup can hamper reproduction and insight into this is making genetic diagnosis and counselling increasingly important. This fully updated textbook continues the clear structure of the original edition, beginning with a chapter on the basics of genetics and cytogenetics. Genetic causes of infertility and the effect of epigenetics and transposons on fertility are discussed in detail. Several new chapters are included in this edition, reflecting the advances of the field, including preconception genetic analysis and screening in IVF and mitochondrial genetics. Combining genetics, reproductive biology and medicine, this is an essential text for practitioners in reproductive medicine and geneticists involved in the field looking to improve their knowledge of the subject and provide outstanding patient care.

Stéphane Viville, Laboratoire de Génétique Médicale de Strasbourg and Laboratoire de diagnostic génétique, Strasbourg
Stéphane Viville is a Professor at the University of Strasbourg. He leads a laboratory of fundamental research at the Laboratoire de génétique médicale (UMRS-1112) Strasbourg. He is a former Chair of the ESHRE Reproductive Genetics Special Interest Group.

Karen D. Sermon, Reproduction and Genetics Research Group, Vrije Universiteit Brussel
Karen D. Sermon is Head of the Reproduction & Genetics Research Group, Vrije Universiteit Brussel, Brussels. She is a former Chair of the ESHRE Reproductive Genetics Special Interest Group and is currently chair-elect for ESHRE (2021-2023) and chair (2023-2025).

Contributors

Karen Sermon, Elia Fernandez Gallardo, Thomas Lefevre, Koen Theunis, Thierry Voet, Ursula Eichenlaub-Ritter, Esther B. Baart, Effrosyni Chavli, Diane Van Opstal, Ashwini Balakrishnan, J. Richard Challiet, Patricia Fauque, Deborah Bourc'his, Svetlana A. Yatsenko, Aleksandar Rajkovic, Stephane Viville, Ozlem Okutman, Juan Jose Guillen, Rita Vassena, Christine De Die-Smulders, Ron van Golde, Claudia Spits, Filippo Zambelli, Jan Traeger-Synodinos, Carmen Rubio Lluesa, Aafke P. A. van Montfoort, Guido de Vert, Wybo Dondorp