Cancer Pain provides a comprehensive, practical guide to the management of pain in cancer patients. Beginning with a discussion of current issues in the control of cancer pain, the initial chapters provide a clear, concise explanation of cancer pain syndromes, an up-to-date understanding of the pathophysiological mechanism and recent developments in creating pre-clinical cancer pain models. The book offers the reader the wide and improved options for management of cancer pain in clinical practice including the use of opioid and non-opioid drugs and the role of non-pharmacological methods in pain control. Subsequent chapters address particular challenges in pain control, such as breakthrough pain, neuropathic cancer pain, as well as pain associated with cancer treatment which, until recently, has not been fully appreciated. Recent issues relating to new adverse side effects to chronic opioid medications such as hyperalgesia and neurotoxicity are explained, and best practice to reduce or avoid them is stated. The book also aims to aid in the overall educational need for young doctors as well as established primary care physicians by highlighting the available tools and the importance of early pain interventions in the overall cancer treatment strategy.
1 Introduction.- 2 Epidemiology of Pain in Cancer.- 3 Recent Advances in Cancer Treatment.- 4 Pharmacogenetics of Pain in Cancer.- 5 Mechanisms of Cancer Pain.- 6 Pre-clinical Cancer Pain Models.- 7 Pain Assessment, Recognizing Clinical Patterns and Cancer Pain Syndromes.- 8 Opioids, their Receptors and Pharmacology.- 9 Critical Appraisal of the Breakthrough Pain in Cancer.- 10 Opioid-induced Hyperalgesia.- 11 The Non-pharmacological and Local Pharmacological Methods of Pain Control.- 12 New Drugs in Management of Pain in Cancer.- 13 Neuropathic Component of Pain in Cancer.- 14 Non-cancer-related Pain in Daily Practice.- 15 Rehabilitation of Cancer Patients: a Forgotten Need?.- 16 Psychosocial Aspects of Cancer Pain.- 17 Spiritual Care and Pain in Cancer.- 18 Interventional Techniques in Cancer Pain: Critical Appraisal.- 19 Challenges for Pain Management in 21st Century.