Physiological Basis of Ventrilatory Support

Description: A truly international work consisting of select contributions from authorities at the forefront of research and practice in mechanical ventilation, this quintessential resource defines the implementation of optimal management procedures for patients requiring respiratory assistance�heightening appreciation of the ventilator's significance in advanced life support while cautioning of potentially detrimental outcomes related to its improper or protracted use.

Advancing the continually evolving understanding of this clinically vital area, Physiological Basis of Ventilatory Support explores underlying physiological and pathophysiological mechanisms elaborates on the intricacies involved in decision making due to the heterogeneity of diseases, extreme variations in patient physiology and response, and complexity of ventilator modes describes the consequences of employing, as well as state-of-the-art methodology for implementing, mechanical ventilation details commonly encountered problems resulting from ventilatory use, including infection, barotrauma, hemodynamic compromise, and lung injury and more!

Packed with well over 5500 references, tables, equations, drawings, and photographs, and elaborately indexed for ready access to information, there is no better hands-on guide for pulmonologists, physiologists, anesthesiologists, intensivists, respiratory therapists, nurses, critical care specialists, and graduate and medical school students involved in the teaching, investigation, or provision of ventilatory support.

Contents:

Physiology Underlying Ventilatory Support

CONTROL OF BREATHING AND RESPIRATORY MUSCLE FUNCTION

Control of Breathing Relevant to Mechanical Ventilation, Magdy Younes and Dimitris Georgopoulos-Loaded Breathing and Dyspnea, Kieran J. Killian-Muscle Function: Basic Concepts, Theodoros Vassilakopoulos, Spyros Zakynthinos, and Charis Roussos-Assessment of Drive/Muscle Function, Rolf D. Hubmayr and Peggy M. Simon--RESPIRATORY MECHANICS--Mechanics of the Lungs and Chest Wall, Stephen H. Loring-Surfactant and Mechanical Ventilation, Alan H. Jobe and Machiko Ikegami-Assessment of Mechanics, Jason H. T. Bates-Work of Breathing During Mechanical Ventilation, Catherine S. H. Sassoon and C. Kees Mahutte--GAS EXCHANGE--Distributions of Alveolar Ventilation and Pulmonary Blood Flow, Josep Roca and Roberto Rodriguez-Roisin-The Effects of Mechanical Ventilation on Oxygen Delivery and Oxygen Consumption, James A. Russell--Consequences of Mechanical Ventilation--VENTILATION-RELATED CONSEQUENCES--Patient-Ventilator Interactions: Dyssynchrony and Imposed Loads, Neil R. MacIntyre-Ventilator-Induced Lung Injury: Mechanisms and Clinical Correlates, Lorraine N. Tremblay, Arthur S. Slutsky, Didier Dreyfuss, and Georges Saumon-Dynamic Hyperinflation, John J. Marini-Heart-Lung Interactions, Michael R. Pinsky--NON-VENTILATION-RELATED CONSEQUENCES--Upper Airway Dysfunction, John E. Heffner-Conditioning of Inspired Gases, Maire P. Shelly-Sedation and Paralysis During Mechanical Ventilation, Luciano Aguilera, Javier Alonso, Anton Arizaga, Thomas E. Stewart, and Jesus Villar--Implementing Ventilatory Support--INITIATING MECHANICAL VENTILATION --Physiological Consequences of Intubation, Steven Deem and Michael J. Bishop-Targets During Mechanical Ventilation, Keith G. Hickling-Monitoring of the Mechanically Ventilated Patient, Robert Shapiro and Robert M. Kacmarek--MODES OF VENTILATORY SUPPORT --Full Ventilatory Support, Theodore W. Marcy-Partial Ventilatory Support, Pierre Aslanian and Laurent J. Brochard-PEEP and CPAP in Severe Airflow Obstruction, Andrea Rossi, Lorenzo Appendini, and Marco V. Ranieri-Positive End-Expiratory Pressure in Acute Respiratory Failure: Pathophysiology and Practical Guidelines, Peter M. Suter and François Lemaire-High-Frequency Ventilation: Principles and Practice, Sergio P. Ribeiro, Lorraine N. Tremblay, and Arthur S. Slutsky-Noninvasive Positive-Pressure Ventilation in Patients with Acute Respiratory Failure, G. Umberto Meduri--ADJUNCTIVE METHODS AND APPROACHES --Extracorporeal Support of Gas Exchange, Antonio Pesenti, Michela Bombino, and Luciano Gattinoni Tracheal Gas Insufflation, Avi Nahum, John J. Marini, and Arthur S. Slutsky-Pharmacological Approach to Hypoxemia in Patients with Acute Respiratory Distress Syndrome, Louis Puybasset and Jean-Jacques Rouby-The Effect of Body Position on Perfusion, Ventilation, and Gas Exchange in Normal and Injured Lungs, Richard K. Albert-Fluid Management and Bronchodilator Therapy During Mechanical Ventilation, David J. Pierson-Liquid Ventilation, Burkhard Lachmann, Astrid Fraterman, and Serge J. C. Verbrugge--Specific Problems in Ventilation --Mechanical Ventilation in Severe Asthma, James W. Leatherman-Barotrauma, Volutrauma, and the Ventilation of Acute Lung Injury, Marcelo B. P. Amato and John J. Marini-Special Problems in Mechanical Ventilation, Robert W. Taylor and R. Philip Dellinger-Discontinuation of Ventilatory Support, Amal Jubran and Martin J. Tobin-Neonatal and Pediatric Ventilation: Physiological and Clinical Perspectives, Alison B. Froese-Clinical Trial Issues in Mechanical Ventilation, Alan H. Morris and Deborah J. Cook