Osteoarthritis

Written by the foremost experts, this text is a comprehensive clinical reference on osteoarthritis. Chapters review current information on the epidemiology, etiopathogenesis, and pathology of osteoarthritis, the biochemistry and molecular and cell biology of articular cartilage, and experimental models of osteoarthritis. Major sections focus on clinical presentations, roentgenologic and laboratory diagnosis, and treatment, including pharmacologic treatment, intra-articular therapy, surgery, arthroscopy, and complementary and alternative medicine. The authors discuss the indications, outcomes, and complications of various orthopaedic procedures. Chapters present orthopaedic approaches to osteoarthritis of various joints— the shoulder, hand, wrist, elbow, hip, knee, foot, ankle, and cervical, thoracic, and lumbar spine.

Table of contents

1 Epidemiology of osteoarthritis by Leena Sharma and Dipali Kapoor
2 Etiopathogenesis of osteoarthritis by A. Robin Poole and Farshid Guilak and Steven B. Abramson
3 Pathology of osteoarthritis by Aubrey J. Hough, Jr.
4 Cell biology, biochemistry, and molecular biology of articular cartilage in osteoarthritis by Linda J. Sandell and Dick Heinegard and Thomas M. Hering
5 Experimental models of osteoarthritis by Margaret M. Smith and Christopher B. Little
6 Molecular genetics of osteoarthritis by John Loughlin and Kay Chapman
7 Osteoarthritis : clinical presentations by Michele M. Hooper and Roland W. Maskowitz
8 Radiologic diagnosis by Garry Cold and Vijay Chandnani and Donald Resnick
9 Magnetic resonance imaging by Charles G. Peterfy and Julie C. DiCarlo and Manish Kothari
10 Ultrasound and alternative imaging outcomes by Helen I. Keen and Paul Emery and Philip G. Conaghan
11 Laboratory findings in osteoarthritis by Roy D. Altman
12 Noninvasive biochemical markers in osteoarthritis by Patrick Garnero
13 Secondary osteoarthritis by H. Ralph Schumacher, Jr. and Lan X. Chen and Joseph Buckwalter
14 Baseline program by Todd Stitik and Marc C. Hochberg
15 The pharmacologic treatment of osteoarthritis by Lee S. Simon and Vibeke Strand
16 Intra-articular therapy by David H. Neustadt and Roy D. Altman
17 Complementary and alternative medicine by Sharon L. Kolasinski
18 Study design and outcome measures in osteoarthritis clinical trials by Vibeke Strand and Marc C. Hochberg
19 General considerations, indications, and outcomes by Victor M. Goldberg