Hiv/aids in South Africa

This definitive textbook covers all aspects of HIV/AIDS in southern Africa, from basic science to medicine, sociology, economics and politics. It has been written by a highly-respected team of southern African HIV experts and provides a thoroughly researched account of the epidemic in the region. The book comprises eight sections, the first of which covers the numbers behind the epidemic, both as evolution and in their current state. This is followed by sections on the science of the virus, including its structure, diagnosis and spread. HIV risk factors and prevention strategies, focal population groups and the impact of AIDS in all aspects of South African life are discussed in the following four sections. The final sections examine the treatment of HIV and AIDS, the politics of AIDS, mathematical modelling and a discussion on the future of AIDS in South Africa.

• Written by highly respected southern African HIV experts at a level that is authoritative without being academic
• Broad scope - everything from medicine and science to sociology, economics and politics
• Broad target audience - medical students, researchers in HIV/AIDS, educated lay persons and political commentators

Contents

Part I. Birth of a Rapidly Growing Epidemic: 1. Introduction Salim Abdool Karim; 2. Overview of the book Salim Abdool Karim and Cheryl Baxter; 3. HIV Infection in South Africa: the evolving epidemic Eleanor Gouws and Quarraisha Abdool Karim; 4. HIV incidence rates in South Africa Eleanor Gouws; Part II. The Virus, the Human Host and Their Interactions: 5. Viral structure, replication, tropism, pathogenesis and natural history Lynn Morris; 6. HIV diagnostics Adrian Puren; 7. Origin, diversity and spread of HIV Carolyn Williamson; 8. Cellular immunity in HIV Clive Gray; Part III. HIV Prevention: Strategies, Successes and Challenges: 9. Reducing sexual risk behaviours Catherine Mathews; 10. Promoting condoms Landon Myer; 11. Preventing mother-to-child transmission Jerry Coovadia; 12. Sexually transmitted infections David Coetzee and Leigh Johnson; 13. Safe blood transfusions Anton Heyns and Johanna Swanevelder; 14. Intravenous drug users Ted Leggett; 15. New prevention strategies under development Salim Abdool Karim; Part IV. Gender in the HIV/AIDS Epidemic: 16. Gender Quarraisha Abdool Karim; 17. Youth Abby Harrison; 18. Women Quarraisha Abdool Karim; 19. Sex workers Gita Ramjee; 20. Population movement and the spread of HIV Mark Lurie; Part V. Impact of AIDS: 21. Health care burden Mark Colvin; 22. Social impact Janet Frohlich; 23. Dual loyalties and conflicts of interest in the HIV/AIDS clinical care landscape Jerome Singh; 24. Standards of care in HIV clinical trials Jerome Singh; 25. Economic impact Alan Whiteside; Part VI. Treating AIDS; 26. Clinical spectrum of AIDS Gary Maartens; 27. TB and HIV Gavin Churchyard and Elizabeth Corbet; 28. Prevention of opportunistic infections in adults Gary Maartens; 29. Nutritional prophylaxis Marianne Visser; 30. Challenges in managing AIDS in South Africa Douglas Wilson and Lara Fairall; 31. Antiretroviral therapy Robin Wood; 32. Challenges of antiretroviral drugs in a developing country Andrew Gray; Part VII. What Does the Future Hold?: 33. A litany of errors post 1994 Nawaal Deane; 34. Models and trends Brian Williams; 35. Conclusion Salim Abdool Karim.

Reviews

'… taken altogether this wealth of information illuminates the path of this dark disease … As you, the reader, page through this book, I hope and trust that you will hear the call to action.' Nelson Mandela

'South Africa possesses the capacity to both curb the epidemic and to minimise its impact - dedicated efforts by its government and civil society are already underway. A wealth of essential evidence is available in this book, making it a valuable contribution to the effort against AIDS in South Africa.' Peter Piot

'… an easy read, targeted at a general audience. … this book is interesting and informative. It is welcomed, and one which will be of interest to many in South Africa and beyond.' Epidemiology and Infection

'This book makes an extraordinary contribution to the growing body of literature on HIV/AIDS in South Africa. The editors bring together an extensive group of researchers who write about the full range of issues associated with the HIV/AIDS epidemic … This collection has been well organised and carefully conceptualised. It is encyclopaedic in nature, and constitutes an extremely valuable resource for those working and researching in the field of HIV/AIDS.' Modern African Studies