Immunology. Clinical Case Studies and Disease Pathophysiology

Description

• 26 real-life cases illustrate the applications of basic immunology in clinical settings
• May be utilized alone or as a companion to Immunology: A Short Course 6th edition by Coico and Sunshine ISBN 9780470081587
• Each case study is introduced by clearly written descriptions of the major immunological disorders
• Full colour photographs and illustrations complement complete presentation of real data
• Includes complete set of problems and discussion questions for each chapter

Table of Contents

Preface.
Dedication.
Introduction.

I. IMMUNODEFICENCY DISEASES.

Evaluation of the Immunodeficient Patient.

A. Primary Immunodeficiency Diseases.

1. X-linked Agammaglobulinemia (Bruton’s Agammaglobulinemia (Susan RS Gottesman).
2. Severe Combined Immunodeficiency Disease (Fabio Candotti).
3. DiGeorge Syndrome (Susan RS Gottesman).
4. Hyper-IgM Syndrome (Warren Strober).
5. Common Variable Immunodeficiency Disease (Warren Strober).
6. Autoimmune Lymphoproliferative Syndrome (ALPS) (Thomas Fleicher).
7. X-Linked Lymphoproliferative Disease (Jeffrey Cohen).
8. Hereditary Angioedema, (Milon Basta and Walter Reed).

B. Secondary Immunodeficiency Diseases.

9. Acquired Immunodeficiency Syndrome (AIDS) (Frank Maldarelli).

II. IMMEDIATE HYPERSENSITIVITY AND MAST CELL DISORDERS.

Introduction.

10. Mastocytosis (Cem Akin).
11. Anaphylaxis (Robert Hamilton).
12. Asthma (Dale Umetsu).
13. The Vasculitides (Michael Sneller).

III. AUTOIMMUNE DISORDERS.

Overview of Autoimmune Disorders and Mechanisms of Tolerance.

14. Myasthenia Gravis (Angela Vincent and John Radcliffe).
15. Multiple Sclerosis (Roland Martin).
16. Diabetes Mellitus (Kristina Rother).
17. Celiac Disease (Warren Strober).
18. Inflammatory Bowel Disease (Peter Mannon).
19. Psoriasis (Bruce Strober).
20. IgA Nephropathy and Kidney Transplantation (Roz Mannon).
21. Rheumatoid Arthritis (Barbara Mittleman).
22. Systemic Lupus Erythematosus (Gabor Illei).
23. Scleroderma (Atsushi Kitani).

IV. MALIGNANCIES OF THE LYMPHOID SYSTEM.

Classification of Lymphoid Malignancies.

24. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (Susan RS Gottesman).
25. Follicular Lymphoma (Susan RS Gottesman).
26. Plasma Cell Neoplasms (Susan RS Gottesman).

V. Appendix - Immunological Techniques Used in the Study of Patients with Disease.

Index.