Biology and Diseases of the Ferret

Description

Biology and Diseases of the Ferret, Third Edition has been thoroughly revised and updated to provide a current, comprehensive reference on the ferret. Encyclopedic in scope, it is the only book to focus on the characteristics that make the ferret an important research animal, with detailed information on conditions, procedures, and treatments. Offering basic information on biology, husbandry, clinical medicine, and surgery, as well as unique information on the use of ferrets in biomedical research, Biology and Diseases of the Ferret is an essential resource for investigators using ferrets in the laboratory and for companion animal and comparative medicine veterinarians.

The Third Edition adds ten completely new chapters, covering regulatory considerations, black-footed ferret recovery, diseases of the cardiovascular system, viral respiratory disease research, morbillivirus research, genetic engineering, hearing and auditory function, vision and neuroplasticity research, nausea and vomiting research, and lung carcinogenesis research. Additionally, the anesthesia, surgery, and biomethodology chapter has been subdivided into three and thoroughly expanded. The book also highlights the ferret genome project, along with the emerging technology of genetically engineered ferrets, which is of particular importance to the future of the ferret as an animal model in research and will allow the investigation of diseases and their genetic basis in a small, easily maintained, non-rodent species.

Table of Contents

Contributors
Preface

Section I Biology and Husbandry 3

• Chapter 1 Taxonomy, History, and Use 5
  James G. Fox
• Chapter 2 Anatomy of the Ferret 23
  Howard Evans and Nguyen Quoc An
• Chapter 3 Neuroanatomy of the Ferret Brain with Focus on the Cerebral Cortex 69
  Christopher D. Kroenke, Brian D. Mills, Jaime F. Olavarria, and Jeffrey J. Neil
• Chapter 4 Physiology of the Ferret 81
  Mark T. Whary
• Chapter 5 Nutrition of the Ferret 123
  James G. Fox, Carrie S. Schultz, and Brittany M. Vester Boler
• Chapter 6 Housing and Management 145
  James G. Fox and Rosemary Broome
• Chapter 7 Normal Clinical and Biological Parameters 157
  James G. Fox
• Chapter 8 Growth and Reproduction 187
  James G. Fox, Judith A. Bell, and Rosemary Broome
• Chapter 9 Regulatory Considerations 211
  Robert P. Marini
• Chapter 10 Recovery of the Black-Footed Ferret 219
  Rachel Santymire, Heather Branvold-Faber, and Paul E. Marinari

Section II Diseases and Clinical Applications 233

• Chapter 11 Physical Examination, Preventive Medicine, and Diagnosis in the Ferret 235
  Robert P. Marini
• Chapter 12 Anesthesia 259
  Jeff C. Ko and Robert P. Marini
• Chapter 13 Surgery 285
  Stephen J. Mehler
• Chapter 14 Diseases of the Hematopoietic System 311
  Jörg Mayer, Susan E. Erdman, and James G. Fox
• Chapter 15 Diseases of the Genitourinary System 335
  James G. Fox and Judith A. Bell
• Chapter 16 Diseases of the Gastrointestinal System 363
  Kirk J. Maurer and James G. Fox
• Chapter 17 Diseases of the Endocrine System 377
  Cassandra L. Miller, Robert P. Marini, and James G. Fox
• Chapter 18 Diseases of the Cardiovascular System 401
  Robert A. Wagner
• Chapter 19 Other Systemic Diseases 421
  James G. Fox
• Chapter 20 Viral Diseases of Ferrets 439
  Matti Kiupel and David Perpiñán
• Chapter 21 Bacterial and Mycoplasmal Diseases 519
  Alton G. Swennes and James G. Fox
• Chapter 22 Parasitic Diseases 553
  Mary M. Patterson, James G. Fox, and Mark L. Eberhard
• Chapter 23 Mycotic Diseases 573
  James G. Fox
• Chapter 24 Neoplastic Diseases 587
  James G. Fox, Sureshkumar Muthupalani, Matti Kiupel, and Bruce Williams

Section III Research and Applications 627

• Chapter 25 The Ferret in Viral Respiratory Disease Research 629
  Deborah R. Taylor
• Chapter 26 The Ferret in Morbillivirus Research 641
  Veronika von Messling
• Chapter 27 Use of the Ferret in Cardiovascular Research 653
  James P. Morgan
• Chapter 28 Genetic Engineering in the Ferret 665
  Xingshen Sun, Ziying Yan, Xiaoming Liu, Alicia K. Olivier, and John F. Engelhardt
• Chapter 29 Hearing and Auditory Function in Ferrets 685
  Fernando R. Nodal and Andrew J. King
• Chapter 30 The Ferret as a Model for Visual System Development and Plasticity 711
  Jitendra Sharma and Mriganka Sur
• Chapter 31 The Ferret in Nausea and Vomiting Research: Lessons in Translation of Basic Science to the Clinic 735
  Nathalie Percie du Sert and Paul L.R. Andrews
• Chapter 32 The Ferret in Lung Carcinogenesis and Nutritional Chemoprevention Research 779
  Xiang-Dong Wang and Chun Liu

Index 795

Author Information

James G. Fox, DVM, MS, DACLAM, is Professor and Director at MIT’s Division of Comparative Medicine, as well as Chair of ACLAM’s publications committee. He is also an Adjunct Professor at Tufts University’s Cummings School of Veterinary Medicine and at the University of Pennsylvania’s School of Veterinary Medicine.

Robert P. Marini, DVM, DACLAM, is Assistant Director and Chief of Veterinary Surgical Resources at MIT’s Division of Comparative Medicine and Lecturer in Health, Science and Technology, also at MIT.