Practical Flow Cytometry in Haematology Diagnosis

Description

Practical Flow Cytometry in Haematology Diagnosis Dr Mike Leach, Dr Mark Drummond and Dr Allyson Doig Department of Haematology, Gartnavel General Hospital, Glasgow, UK Haematology Department, Beatson West of Scotland Cancer Centre, Glasgow, UK Department of Haematology, Gartnavel Hospital, Glasgow, UK The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditions Carefully chosen real-life cases in each chapter, complemented by high quality morphological images Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide. Titles of related interest Ortolani: Flow Cytometry of Hematological Malignancies (2011) ISBN: 978-1-4443-3588-0 Kottke-Marchant: Laboratory Hematology Practice (2012) ISBN: 978-1-4051-6218-0

Table of contents

Acknowledgements.
1 Introduction.
2 Principles of Flow Cytometry.
3 Limitations.
4 Normal blood and bone marrow populations.
5 Acute Leukaemia.
6 Chronic lymphoid leukaemias and exfoliating lymphoma.
7 Myelodysplastic Syndromes and Myeloproliferative Neoplasms.
8 Disorders of plasma cells.
9 Minimal residual disease.
10 Red cells, leucocytes and platelets.
11 Reactive and non-neoplastic phenomena.
Index.