Vaccinology. an Essential Guide

Description

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens.

Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes.

Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Table of Contents

Contributor list
Preface

1 The History of Vaccine Development and The Diseases They Prevent
Martin G. Myers

2 Vaccine Development Pathway
David W. C. Beasley

3 Control and Eradication of Human and Animal Diseases by Vaccination
Nigel Bourne and Gregg N. Milligan

4 Pathogenesis of infectious diseases and mechanisms of immunity
Jere W. McBride and David H. Walker

5 The host immune response, protective immunity, and correlates of protection
Gregg N. Milligan

6 Adjuvants: Making vaccines immunogenic
Gregg N. Milligan

7 Discovery and basic science phase of vaccine development
Gavin C. Bowick

8 Microbial-based and Material-based Vaccine Delivery Systems
Alfredo G. Torres, Jai S. Rudra, and Gregg N. Milligan

9 Licensed Vaccines for humans
Alan D.T. Barrett

10 Veterinary vaccines
A. Paige Adams

11 Development of Vaccines for Microbial Diseases
Dennis W. Trent and David W.C. Beasley

12 Regulatory Path to Vaccine Licensure
Dennis W. Trent

13 Veterinary vaccines: Regulations and impact on emerging infectious diseases
A. Paige Adams

14 Vaccine Manufacturing
Dirk E Teuwen and Alan D.T. Barrett

15 Clinical Evaluation of Vaccines
Richard E. Rupp and Bridget E. Hawkins

16 Vaccine Recommendations & Special Populations
Richard E. Rupp and Bridget E. Hawkins

17 Vaccine Safety
Dirk E. Teuwen and Alan D.T. Barrett

18 Understanding and Measuring Dynamics of Infectious Disease Transmission
Christine M. Arcari

19 Vaccines from a global perspective
Alan D.T. Barrett and Bridget E. Hawkins

20 Political, Ethical, Social and Psychological Aspects of Vaccinology
Caroline M. Poland, Robert M. Jacobson, Douglas J. Opel, Edgar K. Marcuse, Gregory A. Poland

Index