Neuro-Oncology

Description

Cancer imposes daunting effects on the nervous system

Brain cancer is one of the most devastating diagnoses a physician can deliver. Cancer of the nervous system can take many different forms. Treatment is specific to the type of malignancy, its location in the nervous system and, increasingly, its molecular characteristics. The challenges manifest further when management choices need to be made, and multidisciplinary approaches are required. Additional complexities arise in children, where the developing neurological system requires more sensitive treatment.

Neuro-oncology unmasks the complexities to provide a straightforward guide to cancers of the nervous system. Following a general approach to diagnosis and treatment, the clinical aspects of specific cancer types in adults and children are explained in practical terms. A final section considers the effect of system cancer on the nervous system and the side effects of treatment.

Clinical in approach, practical in execution, Neuro-oncology will help you diagnose and manage your patients more effectively.

The Neurology in Practice series provides clinical 'in the office' or 'at the bedside' guides to effective patient care for neurologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature:

• Algorithms and guidelines where they are appropriate
• 'Tips and Tricks' boxes – hints on improving outcomes
• 'Caution' warning boxes – hints on avoiding complications
• 'Science Revisited' – quick reminder of the basic science principles
• Summaries of key evidence and suggestions for further reading

Table of Contents

• List of Contributors
• Foreword
• Preface
• Acknowledgements

Section I: Overview and General Aspects of Theory

• 1. Diagnosis of Brain Tumors: Clinical and Radiographic
  Isabel Arrillaga-Romany, Eudocia Quant Lee and Patrick Y. Wen
• 2. Epidemiology and Etiology
  Melissa L. Bondy, Yanhong Liu and Michael Scheurer
• 3. General Aspects of Surgery
  Brian Williams, Robert Louis and Mark Shaffrey
• 4. General Approach to Radiation Oncology
  Jennifer S. Yu and Daphne Haas-Kogan
• 5. General Aspects of Chemotherapy including "Biologic Agents"
  Jethro Hu and Santosh Kesari

Section II: Adult Nervous System Tumors

• 6. Malignant Gliomas in Adulthood
  Michael Ivan, Matthew Tate, and Jennifer Clarke
• 7. LGG and Oligodendrogliomas in Adulthood
  Derek R Johnson and Kurt A. Jaeckle
• 8. Ependymomas
  Kanwal P.S. Raghav and Mark Gilbert
• 9. Germ Cell Tumors and Other Pineal Region Tumors
  Geneviève Legault and Jeffrey C. Allen
• 10. Sellar Tumors: Pituitary Adenomas and Craniopharyngiomas
  Robert G. Louis and Robert Dallapiazza and John Jane Jr.
• 11. Meningiomas
  Wendy Sherman and Jeffrey Raizer
• 12. Intradural Spinal Cord Tumors
  Ben Shofty, Akiva Korn, Zvi Lidar and Shlomi Constantini

Section III: Pediatric Brain Tumors

• 13. Gliomas in Childhood
  Bruce H. Cohen
• 14. Embryonal Tumors
  Roger J. Packer
• 15. Infantile Brain Tumors
  Alyssa Reddy

Section IV: Systemic Concerns to the CNS and Treatment Sequelea

• 16. Primary Central Nervous System Lymphomas
  Jerome Graber and Antonio M.P. Omuro
• 17. Intracranial Metastases
  Mary Welch and Thomas J. Kaley
• 18. Spinal Cord Compression
  Melike Mut
• 19. Leptomeningeal Metastases
  Sean Grimm and Marc Chamberlain
• 20. Immune Mediated Paraneoplastic Neurologic Disorders: An Overview
  Myrna R. Rosenfeld and Josep Dalmau
• 21. Neurotoxicity of Radiation Therapy and Chemotherapy
  Eudocia C. Quant Lee

Author Information

Roger J. Packer, MD, Center for Neuroscience and Behavioral Medicine, Brain Tumor Institute, Gilbert Family Neurofibramatosis Institute, Children's National, Washington, DC, USA

David Schiff, MD, Departments of Neurology, Neurological Surgery, and Medicine, University of Virginia Health Science Center, Charlottesville, VA, USA