The discovery of Lyme disease, biologically better termed Lyme borreliosis, has provided scientists with a tremendous opportunity to elucidate pathophysiologic mechanisms in borrelial infections. Large, carefully designed, and mostly prospective clinico-epidemiologic studies are the basis for the evidence-based review chapters that constitute Lyme Borreliosos: Epidemiology and Clinical Applications. Clinicians will find herein a body of knowledge that will facilitate their management of patients, as well as arm them with authoritative information they can use to dispel the myths about tick-borne infections that have crept into the popular knowledge.
Table of Contents
1 THE EMERGENCE AND EPIDEMIOLOGY OF LYME BORRELIOSIS IN EUROPE AND NORTH AMERICA (Sunil K. Sood, Susan O’Connell, and Klaus Weber).
2 THE SPIROCHETES AND VECTOR TICKS OF LYME BORRELIOSIS IN NATURE (Joseph Piesman and Pierre-François Humair).
3 EARLY LYME BORRELIOSIS (Vijay K. Sikand and Robert R. Müllegger).
4 LYME CARDITIS (Fadi A. Haddad and Sunil K. Sood).
5 NERVOUS SYSTEM LYME BORRELIOSIS (John J. Halperin and Leif Dotevall).
6 LYME ARTHRITIS (Frank Dressler, Patricia I. Irigoyen, Norman T. Ilowite, and Hans-Iko Huppertz).
7 BORRELIAL LYMPHOCYTOMA AND ACRODERMATITIS CHRONICA ATROPHICANS (Mark B. Salzman and Robert R. Müllegger).
8 LYME BORRELIOSIS COINFECTIONS WITH ANAPLASMA AND BABESIA (Paul M. Lantos and Peter J. Krause).
9 THE ROLE OF CULTURE AND NUCLEIC ACID AMPLIFICATION IN DIAGNOSIS OF LYME BORRELIOSIS (Gary P. Wormser and Guiqing Wang).
10 SERODIAGNOSIS OF LYME BORRELIOSIS (Barbara J. B. Johnson, Maria E. Aguero-Rosenfeld, and Bettina Wilske).
11 PROGNOSIS OF PERSONS WITH LYME BORRELIOSIS (Eugene D. Shapiro and Sunil K. Sood).
12 PREVENTION OF LYME BORRELIOSIS (Sunil K. Sood).