Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine. Current and Future Industrial Applications

Description

Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine covers a wide range of knowledge on cyclodextrins, from an overview of molecular and supramolecular aspects of cyclodextrin physicochemistry, to the latest outcomes in cyclodextrin use and future possibilities in the employment of these systems. This book focuses on the derivatives and physicochemical and biological properties of cyclodextrins, and considers drug delivery through topical, mucosal, and oral via cyclodextrin complexes.

Table of Contents

SECTION 1: CYCLODEXTRINS: HISTORY, PROPERTIES AND APPLICATIONS, CURRENT STATUS.

1 CYCLODEXTRINS AND THEIR INCLUSION PROPERTIES (Dominique DUCHENE, UMR CNRS 8612, Physico-Chimie – Pharmacotechnie – Biopharmacie, Faculté de Pharmacie, Université Paris-Sud, 5 rue Jean Baptiste Clément, 92290 Châtenay Malabry, France).

2 CYCLODEXTRINS AS POTENTIAL EXCIPIENTS IN PHARMACEUTICAL FORMULATIONS: SOLUBILIZING AND STABILIZING EFFECT (Alka AHUJA, Sanjula BABOOTA, Javed ALI, Gulam MUSTAFA, Department of Pharmacy, Oman Medical College, Muscat, Oman; Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi 110062, India).

3 CYCLODEXTRINS AS BIOAVAILABILITY ENHANCERS (Nevin ÇELEBI, Füsun ACARTÜRK, Gazi University Faculty of Pharmacy Department of Pharmaceutical Technology Besevler-Ankara, Turkey).

4 CYCLODEXTRINS AS SMART EXCIPIENTS IN POLYMERIC DRUG DELIVERY SYSTEMS (Agnese MIRO, Francesca UNGARO, Fabiana QUAGLIA, Department of Pharmaceutical and Toxicological Chemistry, Via D. Montesano 49- 80131 Napoli – Italy).

5 RECENT FINDINGS ON SAFETY PROFILES OF CYCLODEXTRINS, CYCLODEXTRIN CONJUGATES AND POLYPSEUDOROTAXANES (Hidetoshi ARIMA, Keiichi MOTOYAMA, Tetsumi IRIE; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan).

6 REGULATORY STATUS OF CYCLODEXTRINS IN PHARMACEUTICAL PRODUCTS (A. Atilla HINCAL, Hakan EROGLU, Erem BILENSOY, IDE Drug Regulatory Affairs, Education, Consultancy Ltd.Co., Ankara-Turkey; Professor Emeritus of Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara -Turkey).

7 CYCLODEXTRINS IN THE COSMETIC FIELD (Nilüfer TARIMCI, Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Tandogan-Ankara, Turkey).

8 CYCLODEXTRIN ENHANCED DRUG DELIVERY THROUGH MUCUS MEMBRANES (Phatsawee JANSOOK, Marcus E. BREWSTER, Thorsteinn LOFTSSON, Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland).

9 APPLICATIONS OF CYCLODEXTRINS FOR SKIN FORMULATION AND DELIVERY (Amelie BOCHOT, Geraldine PIEL, UMRCNRS 8612 Physicochemical, pharmaceutical technology and biopharmacy, School of Pharmacy University Paris-Sud 11, France.
Pharmaceutical technology, Department of Pharmacy, University of Liège, Belgium).

10 ORAL DRUG DELIVERY WITH CYCLODEXTRINS (Francisco VEIGA, Ana Rita FIGUEIRAS, Amelia VIEIRA, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal).

SECTION 2: NOVEL AND SPECIALIZED APPLICATIONS OF CYCLODEXTRINS.

11 AMPHIPHILIC CYCLODEXTRINS: SYNTHESIS AND CHARACTERIZATION (Florent PERRET, Hélène PARROT-LOPEZ, Université de Lyon, F-69622, Lyon, France ; Université Lyon 1, Villeurbanne, CNRS-UMR 5246, Institut de Chimie et Biochimie Moléculaire et Supramoléculaire, Équipe de Chimie Supramoléculaire Appliquée).

12 GENE DELIVERY WITH CYCLODEXTRINS (Véronique WINTGENS, Catherine AMIEL, Institut de Chimie et Matériaux Paris Est, Systèmes Polymères Complexes, 2 rue H. Dunant 94320 Thiais France).

13 TARGETED CYCLODEXTRINS (Stefano SALMASO, Fabio SONVICO, 1Department of Pharmaceutical Sciences, University of Padua, Via F. Marzolo 5 - 35131 Padova, ITALY; Department of Pharmacy, University of Parma, Viale Usberti 27/a – 43100, Parma, ITALY).

14 CYCLODEXTRINS AND BIOTECHNOLOGICAL APPLICATIONS (Amit SINGH, Abhishek KALER, Vachan SINGH, Rachit PATIL, Utam C. BANERJEE, Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar-160 062, India).

15 CYCLODEXTRINS AND CELLULAR INTERACTIONS (Justin M. DREYFUSS, Steven B. OPPENHEIMER, Center for Cancer and Developmental Biology, California State University Northridge, 18111 Nordhoff St. Northridge, CA 91330-8303, USA).

16 CYCLODEXTRIN-BASED HYDROGELS (Carmen ALVAREZ-LORENZO, Maria D. MOYA-ORTEGA, Thorsteinn LOFTSSON, Angel CONCHEIRO, Juan J. TORRES-LABANDEIRA, Departamento de Farmacia y Tecnologia Farmaceutica, Facultad de Farmacia, Universidad de Santiago de Compostela, 15782-Santiago de Compostela, Spain; Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland).

17 CYCLODEXTRIN NANOSPONGES AND THEIR APPLICATIONS (Francesco TROTTA, Dipartimento di Chimica I.F.M., Università di Torino, Via Pietro Giuria 7, 10125 Torino – Italy).

18 PHOTODYNAMIC TUMOR THERAPY WITH CYCLODEXTRIN NANOSSEMBLIES (Antonino MAZZAGLIA, CNR-Istituto per lo Studio dei Materiali Nanostrutturati, ISMN-CNR, c/o Dipartimento di Chimica Inorganica, Chimica Fisica e Chimica Analitica, Università di Messina, Salita perone 31, 98166 Messina, Italy).

19 SUGAMMADEX: A CYCLODEXTRIN BASED NOVEL FORMULATION AND MARKETING STORY (François DONATI, Departement of Anesthesiology, Université de Montréal, Hôpital Maisonneuve-Rosemont, Montréal, Québec, Canada).

20 CYCLODEXTRINS AND POLYMER NANOPARTICLES (Dominique DUCHENE, Ruxandra GREF, UMR CNRS 8612, Physico-Chimie – Pharmacotechnie – Biopharmacie, Faculté de Pharmacie, Université Paris-Sud, 5 rue Jean Baptiste Clément, 92290 Châtenay Malabry, France).

Author Information

Erem Bilensoy, PhD, is a Professor of Pharmaceutical Technology at Hacettepe University in Turkey. Dr. Bilensoy has published more than forty articles in international peer-reviewed journals as well as six book chapters on cyclodextrins.