Principles of Biochemistry (International Student Version)

Description

Voet, Voet, and Pratt’s Principles of Biochemistry, challenges students to better understand the chemistry behind the biological structure and reactions occurring in living systems. The Third Edition continues this tradition, and additionally incorporates coverage of recent research and an expanded focus on preparing and supporting students throughout the course. With the addition of new conceptual assessment content to WileyPLUS, students have the opportunity to assess their conceptual understanding of key introductory biochemistry concepts and retrain themselves on their misconceptions.

Hallmark Features

• Author reputation – authors are well-known and highly regarded teachers and researchers, and bring the highest level of accuracy, currency and scholarship to the book
• Balanced coverage, explaining the chemistry behind the biology
• Grounding in chemistry provides students with an understanding of reactions at the molecular level and helps students see patterns and the "big picture."
• Includes the most up-to-date coverage, particularly in areas impacting upon human health and disease

New to this edition

• Chapter 13 (Biochemical Signaling) is a new chapter that focuses solely on communications within and between cells.
• Chapter 14 (Introduction to Metabolism) includes:
• A new discussion of vitamins, minerals, and macronutrients
• Expanded coverage of DNA chip technology and applications
• Old Ch 28 (Protein Function Part II) is incorporated into other chapters.
• Updating throughout (genomics, proteomics, and more).
• New end-of-chapter problems with complete solutions have been added.
• Learning objectives and checkpoints incorporated within the chapters.
• New nutritional applications/examples incorporated into metabolism.
• New Test Bank featuring a greater variety of thought-provoking conceptual questions
• New conceptual assessment material with detailed feedback, from University of Alberta, has been incorporated into WileyPLUS .

Table of Contents

• PART I: INTRODUCTION.
• Chapter 1. Introduction to the Chemistry of Life.
• Chapter 2. Water.

• PART II: BIOMOLECULES.
• Chapter 3. Nucleotides, Nucleic Acids, and Genetic Information.
• Chapter 4. Amino Acids.
• Chapter 5. Proteins: Primary Structure.
• Chapter 6. Proteins: Three-Dimensional Structure.
• Chapter 7. Protein Function Part I: Myoglobin and Hemoglobin.
• Chapter 8. Carbohydrates.
• Chapter 9. Lipids and Biological Membranes.
• Chapter 10. Membrane Transport.

• PART III: ENZYMES.
• Chapter 11. Enzymatic Catalysis.
• Chapter 12. Enzyme Kinetics, Inhibition, and Regulation.

• PART IV: METABOLISM.
• Chapter 13. Biochemical Signaling
• Chapter 14. Introduction to Metabolism.
• Chapter 15. Glucose Catabolism.
• Chapter 16. Glycogen Metabolism and Gluconeogenesis.
• Chapter 17. Citric Acid Cycle.
• Chapter 18. Electron Transport and Oxidative Phosphorylation.
• Chapter 19. Photosynthesis.
• Chapter 20. Lipid Metabolism.
• Chapter 21. Amino Acid Metabolism.
• Chapter 22. Mammalian Fuel Metabolism: Integration and Regulation.
• Chapter 23. Nucleotide Metabolism.

• PART V: GENE EXPRESSION AND REPLICATION.
• Chapter 24. Nucleic Acid Structure.
• Chapter 25. DNA Replication, Repair, and Recombination.
• Chapter 26. Transcription and RNA Processing.
• Chapter 27. Translation.
• Chapter 28. Regulation of Gene Expression.
• Chapter 29. Protein Function Part II: Cytoskeletal and Motor Proteins and Antibodies.

• Appendix.
• Bioinformatics Exercises.
• Answers to Bioinformatics Exercises.
• Solutions to Problems.
• Glossary.
• Guide to Media Resources.
• Index.

Author

Donald Voet received a B.S. in Chemistry from the California Institute of Technology, a Ph.D. in Chemistry from Harvard University with William Lipscomb, and did postdoctoral research in the Biology Department at MIT with Alexander Rich. Upon completion of his postdoctoral research, Don took up a faculty position in the chemistry Department at the University of Pennsylvania where, for the past 38 years, he has taught a variety of biochemistry courses as well as general chemistry. His major area of research is the X-ray crystallography of molecules of biological interest. he has been a visiting scholar at Oxford University, The University of California at San Diego, and the Weizmann Institute of Science in Israel. Together with Judith G. Voet, he is Co-Editor-in-Chief of the journal biochemistry and Molecular Biology Education. He is a member of the Education Committee of the International Union of biochemistry and Molecular Biology. His hobbies include backpacking, scuba diving, skiing, travel, photography, and writing biochemistry textbooks.

Judith ('Judy") Voet received her B.S. in Chemistry from Antioch College and her Ph.D. in Biochemistry from Brandeis University with Robert H. Abeles. She has done postdoctoral research at the University of Pennsylvania, Haverford College, and the Fox Chase Cancer Center. Her main area of research involves enzyme reaction mechanisms and inhibition. She taught biochemistry at the University of Delaware before moving to Swarthmore College. She taught There for 26 years, reaching the position of James H. Hammons Professor of chemistry and Biochemistry before going on "permanent sabbatical leave." She has been a visiting scholar at Oxford University, University of California, San Diego, University of Pennsylvania, and the Weizmann Institute of Science, Israel. She is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. She has been a member of the Education and Professional Development Committee of the American Society for Biochemistry and Molecular Biology as well as the Education Committee of the International Union of Biochemistry and Molecular Biology. Her hobbies include biochemistry and Molecular biology. Her hobbies include hiking, backpacking, scuba diving, and tap dancing.

Charlotte Pratt received her B.S. in Biology from the University of Notre Dame and her Ph.D. in Biochemistry from Duke University under the direction of Salvatore Pizzo. Although she originally intended to be a marine biologist, she discovered that Bi8ochemsitry offered the most compelling answers to many 3uesitns about biological structure-function relationships and the molecular basis for human health and disease. She conducted postdoctoral researching the Center for Thrombosis and Hemostasis at the University of North Carolina at Chapel Hill. She has taught at the University of Washington and currently teaches at Seattle Pacific University. In addition to working as an editor of several biochemistry textbooks, she has co-authored Essential Biochemistry and previous editions of Fundamentals of Biochemistry.