Retinoblastoma is the most common cancer of the eye in children. Although it is a rare neoplasm, there are many features that make this malignancy unique. Nationally, the incidence is approximately 4 million children per year. 90% of these cases occur in children under 5 and more than 90% will be cured. The resulting effects of the treatment can be blindness, quality of life after survival, and/or reduced life span. However in the last few years, significant advances have been made, including the development of the first mouse models (2004).
Written for: Pediatric Oncologists; Opthalmologists and Ocular Oncologists; Radiation Oncologists; family practitioners; nursing staff; hematology/oncology fellows; medical school libraries.
Table of contents
Biology of Retinoblastoma.- Epidemiology.- Clinical Features, Diagnosis and Pathology.- Principles of Management of Retinoblastoma: Opthalmologic Therapies.- Principles of Management of Retinoblastoma: Radiation Modalities.- Principles of Management of Retinoblastoma: Chemotherapy.- Treatment of Retinoblastoma.- Treatment of Extraocular and Metastatic Retinoblastoma.- Long-term Effects and Second Malignancies.- Cognitive and Functional Development.- Index.