Transfusion and Transplantation Science (Fundamentals of Biomedical Science)

ABOUT THIS BOOK

• A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists
• Content carefully developed to support the reader in demonstrating the competencies required during the study of biomedical science at both undergraduate and postgraduate level
• Case studies and other examples enrich the text, firmly rooting the text in the context of clinical and biomedical practice
• The striking full-colour presentation engages the reader, and presents the many illustrations and photographic images to best effect
• An Online Resource Centre contains a range of additional materials to augment the printed text, including a fully interactive Digital Microscope with a range of cell and tissue images for examination

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.

Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped.

The series:
· Understands the complex roles of Biomedical Scientists in the modern practice of medicine
· Understands the development needs of employers and the Profession
· Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine
· Places the theoretical aspects of Biomedical Science in their practical context

The science of transfusion and transplantation demands a multifaceted understanding of immunology, haematology, and genetics from the biomedical scientist. Transfusion and Transplantation Science coherently synthesises the essential concepts of these subjects and presents them within the practical framework of the hospital banking and transplantation centre, thereby furnishing the reader with the knowledge and skills required to specialize in this discipline.

Beginning with an overview of potential immune responses to transfusion and transplantation, the text goes on to explain the aetiology behind these responses with a view to the prediction, diagnosis, and mitigation of adverse effects on the patient. It then outlines issues of quality, but also regulatory and legal concerns, that need to be considered when collecting, preparing, and storing products for transfusion or transplantation.

Online Resource Centre
The Online Resource Centre to accompany Transfusion and Transplantation Science features:

For registered adopters of the book:
· Figures from the book, available to download

For students:
· An interactive Digital Microscope, encouraging the exploration of tissue samples
· Self-assessment modules to help you to check and reinforce understanding of the basic science introduced in each volume
· Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice

Readership: Undergraduates at all levels studying a practice-oriented Biomedical Science degree programme.

TABLE OF CONTENTS

1: Robin Knight: Basic Immunology
2: Malcolm Needs: Human Erythrocyte Antigens: Blood groups
3: Lionel Mohabir: Donors and Donations: Collection and processing
4: Lionel Mohabir: Blood Donation Testing
5: Karen Madgwick and Bill Chaffe: Clinical Use of Blood Components
6: Carol Cantwell and Tony Davies: Blood Transfusion: Compatibility testing and adverse effects
7: Robin Knight: Immune Red Cell Destruction
8: Bridget Montague: Human Leucocyte Antigens [HLA] and their Clinical Significance
9: Geoff Lucas: Human Platelet Antigens [HPA], Human Neutrophile Antigens [HNA], and their Clinical Significance
10: Robert Walters: Stem Cell Banking
11: Richard Lomas: Tissue and Bone Banking
12: John Barker and Joan Jones: Quality Issues

AUTHOR INFORMATION

Edited by Robin Knight, Former Head of the National Blood Service's Red Cell Immunohaematology Division

Contributors:
Robin Knight - Transfusion Science Consultant
Malcolm Needs - National Blood Service
Karen Madgwick - North Middlesex Hospital NHS Trust
Bill Chaffe - East Kent Hospitals University NHS Trust
Carol Cantwell - St Mary's Hospital London
Lionel Mohabir - Welsh Blood Service
Bridget Montague - Leeds Teaching Hospitals NHS Trust
Geoff Lucas - National Blood Service
Robert Walters - North West Wales NHS Trust
Richard Lomas - NHS Blood and Transplant
John Barker - Haematology and Blood Transfusion Department, Queen Elizabeth Hospital
Joan Jones - Welsh Blood Service