Section 1: The basic biology of bacteria, viruses, fungi and parasites
1: The biology of bacteria, Armine Sefton
2: The biology of viruses, Cheuk Yan William Tong, Anna Jeffery-Smith
3: The biology of fungi, Rohini Manuel, Stephanie Smith
4: Parasites and worms, Robert Serafino Wani
5: Host-parasite (microbe) relationship, Caryn Rosmarin
6: Basic immunology, Jonathan Lambourne, Ruaridh Buchanan, Emily Zinser
Section 2: Microbiology, virology and laboratory practice
7: The use of the laboratory in the investigation, management and prevention of infection, Caryn Rosmarin
8: Bacteriology diagnostic methods, Satya Das, Heather Dolphin, Fatima Ahmad, Gurtan Atamturk, Jennifer Henderson, Tim Linehan, Robert Serafino Wani
9: Virological diagnostic methods, Anthony R. Oliver
10: Fungal diagnostics, Rohini Manuel, Shila Seaton
11: Molecular diagnostics, Duncan Clark, Mark Wilks
12: Laboratory quality control and accreditation, Anthony R. Oliver
Section 3: Health and safety
13: Biosafety categorisations and containment levels, Cheuk Yan William Tong
Section 4: Principles of public health in relation to communicable diseases
14: Key communicable diseases of public health significance and UK legislations, Marina Basarab
15: Vaccine preventable diseases, Cheuk Yan William Tong
Section 5: Infection prevention and control
16: Common organisms responsible for hospital acquired infection, Martina Cummins, Jacob Geroge
17: The concept of chain of infection and infection control principles, Martina Cummins, Jacob George
18: Antimicrobial stewardship, Caoimhe NicFhogartaigh, Sarfaraz Ameen
19: Tools in infection prevention and control, Martina Cummins, Stephanie Smith
20: Sterilisation and decontamination, Martina Cummins, Sylvia Martin
Section 6: Important clinical syndromes
21: Sepsis, Mark Melzer
22: Pyrexia of unknown origin, Mark Melzer
23: Blood borne virus infections, Cheuk Yan William Tong
24: Tuberculosis and other mycobacterial infections, Simon Tiberi
25: Multisystem infections, Mark Melzer
26: Cardiovascular infections, Satya Das, Robert Serafino Wani
27: Skin and soft tissue infections, Caoimhe NicFhogartaigh, Rohma Ghani
28: Bone and joint infections, Jayshree Dave, Rohma Ghani
29: Upper and lower respiratory tract infections, Simon Tiberi
30: Gastro-intestinal, hepatic, pancreatic and biliary infections, Michael Millar, Anna Riddell, Cheuk Yan William Tong
31: Urinary tract and genital infections including Sexually Transmitted Infections, Jayshree Dave, Cheuk Yan William Tong
32: Neurological infections, Caryn Rosmarin
33: Ocular infections, Caryn Rosmarin, Ruaridh Buchanan
34: Device-associated infections, Michael Millar
35: Zoonotic infections, Caoimhe NicFhogartaigh, Marta Gonzalaz Sanz
36: Exanthemata, Cheuk Yan William Tong
37: Pregnancy-associated infections, Michael Millar, Anna Riddell
38: Infections in neonates and young infants, Michael Millar, Steve Kempley
39: Infections in immunocompromised hosts, Jonathan Lambourne, Marta Gonzalaz Sanz, Anna Riddell
40: Post-infection syndromes, Sherine Thomas
Section 7: Understanding use of antimicrobial agents
41: Mechanism of antimicrobials, Armine Sefton, Ruaridh Buchanan
42: Use of antimicrobials and toxicity, Armine Sefton
43: Mechanism of antimicrobial resistance, David Wareham, Ruaridh Buchanan
44: Methods to detect antimicrobial resistance, David Wareham, Lynette Phee
45: The role of immunotherapy, Jonathan Lambourne, Ruaridh Buchanan
46: Out-patient parenteral antimicrobial therapy (OPAT), Mark Melzer
47: Anti-virals, Cheuk Yan William Tong
Section 7: Vaccination
48: Different types of vaccines, Cheuk Yan William Tong
49: Vaccination schedules, Gee Yen Shin
50: Vaccination of specific patient groups, Gee Yen Shin
51: Post-exposure prophylaxis, Cheuk Yan William Tong, Jayshree Dave
Section 9: The management of HIV infection
52: Epidemiology and natural history of HIV infection, Chloe Orkin, Palwasha Khan, Sarah Parry
53: Laboratory diagnosis and monitoring of HIV infection, Cheuk Yan William Tong, Anna Jeffery-Smith
54: Therapeutic options for HIV infection, Chloe Orkin, Subathira Dakshina, Palwasha Khan
55: Opportunistic infections in HIV patients, Chloe Orkin, Elizabeth Williams
Section 10: Travel and geographical health
56: Geographical pattern of infectious diseases and prevention for the travellers, Zahir O. E. Babiker, Desmond Hsu
57: Malaria, Zahir O. E. Babiker, Angelina Jayakumar
58: Fever in returned travellers, Zahir O. E. Babiker, Desmond Hsu
Microbiology and virology laboratories provide a diagnostic service that supports the management of patients under the care of front-line clinicians. Despite the significant overlap, laboratory expertise and clinical patient management are traditionally viewed as independent entities. Trainees in the infection disciplines of microbiology, virology, infectious diseases, and tropical medicine have until recently received separate, and as a result, limited training.
To address this problem, the UK replaced the FRCPath Part 1 examination for infectious disease trainees with a combined infection training (CIT) curriculum in 2015. Based on the idea of integration and collaboration within the field, CIT links laboratory expertise to clinical patient management.
Tutorial Topics in Infection for the Combined Infection Training Programme is the first book covering the complete CIT curriculum. Following the format of the CIT certificate examination, each chapter ends with three single best answer multiple choice questions accompanied by in-depth discussions. This extensive content helps students appreciate the breadth of knowledge required, emphasises how the different aspects of the field are related, and is an essential tool for those preparing for the CIT certificate examination.
Written by a multi-disciplinary team of medical microbiologists, virologists, infectious disease physicians, clinical scientists, biomedical scientists, public health specialists, HIV clinicians, and infection control nurses, this well-illustrated and easy to use book offers a unique insight into infectious diseases. It is the perfect primer for further study, a starting point for medical students and professionals wishing to learn more about the different topics within the infection specialty, and ideal for biomedical scientists looking to broaden their clinical understanding of the field beyond the diagnostic test.
- Tutorial style questions and answers.
- Following the format of the CIT certificate examination, the chapters end with three multiple choice questions and an in-depth discussion.
- A primer for the Combined Infection Training (CIT) programme.
- Further readings and useful resources.
- Well-illustrated and easy to use.
Edited by Cheuk Yan William Tong, Consultant in Clinical Virology, Department of Infection, Barts Health NHS Trust, London, UK, Caryn Rosmarin, Consultant in Medical Microbiology, Department of Infection, Barts Health NHS Trust, London, UK, and Armine Sefton, Emerita Professor, Barts Health NHS Trust and the London School of Medicine and Dentistry, Queen Mary University of London, UK.
Dr William Tong was initially trained in paediatrics before he took up the specialty of Virology. He received virology trainings in Hong Kong, London and Newcastle-upon-Tyne. Having worked at Guy's and St. Thomas', and Barts Health NHS Trust, he is currently based at the Royal London Hospital at Whitechapel as clinical lead for the Division of Infection. He has a wide range of interests including viral hepatitis, sexually transmitted infections, HIV, picornaviruses and novel diagnostics, and is the chair of the virology examination panel of the Royal College of Pathologists.
Dr Caryn Rosmarin worked in Emergency Medicine, Clinical Pharmacology and Infectious Disease in South Africa for several years before entering Microbiology. She trained and qualified in Clinical Microbiology both in London and Johannesburg. She is the postgraduate training lead for north-east London and an examiner for the Royal college of Pathologists. She has a wide range of interests including infection control, surgical microbiology, musculoskeletal, vascular and neurosurgical infections, diabetic foot infections, and education.
Armine Sefton trained in general medicine and infectious disease before entering microbiology. In 2003 she became Professor of Medical Microbiology at Barts and the London and remained there until she retired from full-time practice in 2015. Subsequently she returned to work part- time at her local hospital, Princess Alexandra, Harlow. She was course director of the MSc in Clinical Microbiology at Barts and the London for over 20 years. She was an examiner in microbiology for the Royal college of Pathologists, and the chair of their microbiology examination panel from 2008-2012