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An Introduction to Drug Synthesis
Patrick, G.
1ª Edición Enero 2015
Inglés
Tapa blanda
592 pags
1700 gr
null x null x null cm
ISBN 9780198708438
Editorial OXFORD
LIBRO IMPRESO
-5%
71,70 €68,12 €IVA incluido
68,94 €65,50 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
Description
An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development.
Written by an experienced and talented author to complement his existing An Introduction to Medicinal Chemistry, the book illustrates how organic synthesis makes important contributions throughout the drug design and discovery process - from thegeneration of novel drug structures to the improved efficiency of large scale synthesis.
Avoiding excessively detailed descriptions of the underlying synthetic pathways, the book focuses on how synthesis can be used in a strategic way - how and why different synthetic approaches are adopted, and the pros and cons of each.
With examples used extensively to illustrate the concepts presented, An Introduction to Drug Synthesis> is the ideal resource for any pharmaceutical or medicinal chemistry student who needs a thorough understanding of how the concepts of organic synthesis are applied to the development of therapeutic drugs.
Online Resource Centre
An Introduction to Drug Synthesis is supported by an Online Resource Centre featuring:
For registered adopters:
- Figures from the book in electronic format;
For students:
- A suite of multiple-choice questions to support the learning process;
- Additional case studies
- More detailed descriptions of key synthetic reactions, as a source of further reference
Table of Contents
PART A: Concepts
1: The drug discovery process
2: Drug synthesis
3: Retrosynthesis
4: Cyclic systems in drug synthesis
5: The synthesis of chiral drugs
6: Combinatorial and parallel synthesis
PART B: Applications of drug synthesis in the drug development process
7: Synthesis of lead compounds
8: Analogue synthesis in drug design
9: Synthesis of natural products and their analogues
10: Chemical and process development
11: Synthesis of isotopically labelled compounds
PART C: Design and synthesis of selected antibacterial agents
12: Design and synthesis of tetracyclines
13: Erythromycin and macrolide antibacterial agents
14: Quinolones and fluoroquinolones
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