Tissue Engineering. Principles for the Design of Replacement Organs and Tissues

Part 1: Tissue Exchange and Tissue Development
1: The State-of-the-Art in Tissue Exchange
2: Objectives of Tissue Engineering
3: Elements of Tissue Development

Part 2: Tissue Engineering Fundamentals
4: Cell Growth and Differentiation
5: Cell and Tissue Mechanics
6: Cell Adhesion
7: Cell Migration
8: Cell Aggregation and Tissue Equivalents
9: Tissue Barriers to Molecular and Cellular Transport

Part 3: Tissue Engineering Practice
10: Cell Delivery and Recirculation
11: Delivery of Molecular Agents in Tissue Engineering
12: Cell Interactions With Polymers
13: Approaches to Tissue Engineering
14: Case Studies in Tissue Engineering

Appendices
A. Introduction to Polymers
B. Analysis of Molecular Transport
C. Useful Data
D. Nomenclature and Abbreviations

Tissue engineering is a new field of biomedical engineering, in which synthetic materials are used together with biological components such as tissue fragments, cells, proteins to encourage tissue regeneration, regrowth, and repair. This book introduces the principles of tissue engineering in a unique way that is ideally suited for the modern engineering student. A review of developmental biology is presented early in the book, since biological development is the fundamental process of most relevance for tissue engineering. The study of development provides a pathway to basic bioengineering units on cell adhesion, migration, assembly, and transport, which are integrated in the final sections of the book into tissue engineering processes (such as cell delivery, growth factor administration, and polymeric scaffold materials).

W. Mark Saltzman, Goizueta Foundation Professor of Chemical and Biomedical Engineering, Yale University